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Gene Review:

RRS1 - disease resistance protein RRS1

Arabidopsis thaliana

Synonyms: ARABIDOPSIS THALIANA WRKY DOMAIN PROTEIN 52, ATWRKY52, K9E15.2, K9E15_2, RESISTANT TO RALSTONIA SOLANACEARUM 1, ...

Noutoshi, Y. et al., Deslandes, L. et al.

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Disease relevance of SLH1

SLH1 is identical to the R gene RRS1-R of the Arabidopsis ecotype Nd-1, a gene which confers resistance to the bacterial pathogen Ralstonia solanacearum GMI1000 and also functions as an R gene to this pathogen in No-0 [1].

High impact information on SLH1

We demonstrate that SA is required for the slh1 phenotype but not PAD4 or NPR1 [1].
A single amino acid insertion in the WRKY domain of the Arabidopsis TIR-NBS-LRR-WRKY-type disease resistance protein SLH1 (sensitive to low humidity 1) causes activation of defense responses and hypersensitive cell death [1].
Our data suggest that SLH1 disease resistance signaling may be negatively regulated by its WRKY domain in the R protein and that the constitutive defense activation conferred by the slh1 mutation is inhibited by conditions of high humidity [1].

Associations of SLH1 with chemical compounds

Furthermore, the slh1 mutants accumulate callose, autofluorescent compounds and salicylic acid (SA) [1].

Analytical, diagnostic and therapeutic context of SLH1

Sequence analysis of the RRS1 genes present in two homozygous intragenic recombinant lines indicates that several domains of RRS1-R are essential for its resistance function [2].

References

A single amino acid insertion in the WRKY domain of the Arabidopsis TIR-NBS-LRR-WRKY-type disease resistance protein SLH1 (sensitive to low humidity 1) causes activation of defense responses and hypersensitive cell death. Noutoshi, Y., Ito, T., Seki, M., Nakashita, H., Yoshida, S., Marco, Y., Shirasu, K., Shinozaki, K. Plant J. (2005) [Pubmed]
Resistance to Ralstonia solanacearum in Arabidopsis thaliana is conferred by the recessive RRS1-R gene, a member of a novel family of resistance genes. Deslandes, L., Olivier, J., Theulieres, F., Hirsch, J., Feng, D.X., Bittner-Eddy, P., Beynon, J., Marco, Y. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]

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