Gene Review:
SAC6 - fimbrin
Saccharomyces cerevisiae S288c
Synonyms:
ABP67, Fimbrin, YD9302.04C, YDR129C
- Requirement of yeast fimbrin for actin organization and morphogenesis in vivo. Adams, A.E., Botstein, D., Drubin, D.G. Nature (1991)
- Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae. Holtzman, D.A., Yang, S., Drubin, D.G. J. Cell Biol. (1993)
- Isoform-specific complementation of the yeast sac6 null mutation by human fimbrin. Adams, A.E., Shen, W., Lin, C.S., Leavitt, J., Matsudaira, P. Mol. Cell. Biol. (1995)
- Unexpected combinations of null mutations in genes encoding the actin cytoskeleton are lethal in yeast. Adams, A.E., Cooper, J.A., Drubin, D.G. Mol. Biol. Cell (1993)
- Calcium-independent calmodulin requirement for endocytosis in yeast. Kübler, E., Schimmöller, F., Riezman, H. EMBO J. (1994)
- Dominant suppressors of yeast actin mutations that are reciprocally suppressed. Adams, A.E., Botstein, D. Genetics (1989)
- The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents. Ikeda, H., Sasaki, Y., Kobayashi, T., Suzuki, H., Mita, H., Toyota, M., Itoh, F., Shinomura, Y., Tokino, T., Imai, K. Int. J. Oncol. (2005)
- Use of a synthetic lethal screen to identify yeast mutants impaired in endocytosis, vacuolar protein sorting and the organization of the cytoskeleton. Singer-Krüger, B., Ferro-Novick, S. Eur. J. Cell Biol. (1997)
- A new Tetrahymena actin-binding protein is localized in the division furrow. Watanabe, A., Kurasawa, Y., Watanabe, Y., Numata, O. J. Biochem. (1998)
- Genetic analysis of the fimbrin-actin binding interaction in Saccharomyces cerevisiae. Brower, S.M., Honts, J.E., Adams, A.E. Genetics (1995)
- Allele-specific suppression by formation of new protein-protein interactions in yeast. Sandrock, T.M., O'Dell, J.L., Adams, A.E. Genetics (1997)
- Actin mutations that show suppression with fimbrin mutations identify a likely fimbrin-binding site on actin. Honts, J.E., Sandrock, T.S., Brower, S.M., O'Dell, J.L., Adams, A.E. J. Cell Biol. (1994)
- Genetic evidence for functional interactions between actin noncomplementing (Anc) gene products and actin cytoskeletal proteins in Saccharomyces cerevisiae. Vinh, D.B., Welch, M.D., Corsi, A.K., Wertman, K.F., Drubin, D.G. Genetics (1993)
- GCS1, an Arf guanosine triphosphatase-activating protein in Saccharomyces cerevisiae, is required for normal actin cytoskeletal organization in vivo and stimulates actin polymerization in vitro. Blader, I.J., Cope, M.J., Jackson, T.R., Profit, A.A., Greenwood, A.F., Drubin, D.G., Prestwich, G.D., Theibert, A.B. Mol. Biol. Cell (1999)