Gene Review:
MEX67 - Mex67p
Saccharomyces cerevisiae S288c
Synonyms:
P2520, YPL169C, mRNA export factor MEX67
- Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores. Santos-Rosa, H., Moreno, H., Simos, G., Segref, A., Fahrenkrog, B., Panté, N., Hurt, E. Mol. Cell. Biol. (1998)
- Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery. Hieronymus, H., Silver, P.A. Nat. Genet. (2003)
- The DEAD-box protein Dbp5p is required to dissociate Mex67p from exported mRNPs at the nuclear rim. Lund, M.K., Guthrie, C. Mol. Cell (2005)
- The Glc7p nuclear phosphatase promotes mRNA export by facilitating association of Mex67p with mRNA. Gilbert, W., Guthrie, C. Mol. Cell (2004)
- Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export. Strässer, K., Bassler, J., Hurt, E. J. Cell Biol. (2000)
- Cotranscriptional recruitment to the mRNA export receptor mex67p contributes to nuclear pore anchoring of activated genes. Dieppois, G., Iglesias, N., Stutz, F. Mol. Cell. Biol. (2006)
- A Crm1p-independent nuclear export path for the mRNA-associated protein, Npl3p/Mtr13p. Liu, Y., Guo, W., Tartakoff, P.Y., Tartakoff, A.M. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p. Strässer, K., Hurt, E. Nature (2001)
- The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p. Zenklusen, D., Vinciguerra, P., Strahm, Y., Stutz, F. Mol. Cell. Biol. (2001)
- Physical and genetic interactions link the yeast protein Zds1p with mRNA nuclear export. Estruch, F., Hodge, C.A., Rodríguez-Navarro, S., Cole, C.N. J. Biol. Chem. (2005)
- Mex67p mediates nuclear export of a variety of RNA polymerase II transcripts. Hurt, E., Strässer, K., Segref, A., Bailer, S., Schlaich, N., Presutti, C., Tollervey, D., Jansen, R. J. Biol. Chem. (2000)