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Gene Review

FGF17  -  fibroblast growth factor 17

Homo sapiens

Synonyms: FGF-13, FGF-17, Fibroblast growth factor 17, HH20, UNQ161/PRO187
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Disease relevance of FGF17


High impact information on FGF17


Biological context of FGF17


Anatomical context of FGF17


Analytical, diagnostic and therapeutic context of FGF17

  • These studies revealed a significant linear correlation between increasing Gleason sum scores and FGF17 expression using both immunohistochemistry (p < 0.0001, rho = 0.99) and RT-PCR (p = 0.008, rho = 0.99) [2].


  1. FGF17 is an autocrine prostatic epithelial growth factor and is upregulated in benign prostatic hyperplasia. Polnaszek, N., Kwabi-Addo, B., Wang, J., Ittmann, M. Prostate (2004) [Pubmed]
  2. Fibroblast growth factor 17 is over-expressed in human prostate cancer. Heer, R., Douglas, D., Mathers, M.E., Robson, C.N., Leung, H.Y. J. Pathol. (2004) [Pubmed]
  3. Altered HOX and WNT7A expression in human lung cancer. Calvo, R., West, J., Franklin, W., Erickson, P., Bemis, L., Li, E., Helfrich, B., Bunn, P., Roche, J., Brambilla, E., Rosell, R., Gemmill, R.M., Drabkin, H.A. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  4. Expression of the fetal-oncogenic fibroblast growth factor-8/17/18 subfamily in human hematopoietic tumors. Nezu, M., Tomonaga, T., Sakai, C., Ishii, A., Itoga, S., Nishimura, M., Matsuo, Y., Tagawa, M., Nomura, F. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
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