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MeSH Review

Prostatic Hyperplasia

 
 
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Disease relevance of Prostatic Hyperplasia

 

Psychiatry related information on Prostatic Hyperplasia

 

High impact information on Prostatic Hyperplasia

 

Chemical compound and disease context of Prostatic Hyperplasia

 

Biological context of Prostatic Hyperplasia

 

Anatomical context of Prostatic Hyperplasia

 

Gene context of Prostatic Hyperplasia

  • These findings suggest that ligands specific for ERbeta may be useful in the prevention and/or clinical management of prostatic hyperplasia and neoplasia [27].
  • Hey1 colocalizes with AR in the epithelia of patients with benign prostatic hyperplasia, where it is found in both the cytoplasm and the nucleus [28].
  • We found that although DAX-1 is expressed in normal human prostate, its expression is strongly reduced in benign prostatic hyperplasia suggesting that DAX-1 plays a role in limiting AR activity in prostate [29].
  • In the present study, we investigated by use of 35S-labeled antisense RNA probes whether the MCP-1 gene is expressed in tissue specimens of benign prostatic hyperplasia (n = 13) and specimens of prostate carcinoma (n = 8), both of which are characterized by a prominent fibromuscular stroma and inconspicuous inflammatory infiltrates [30].
  • Telomerase, a ribonucleoprotein, is detected in the vast majority of prostate cancer, but not in normal or benign prostatic hyperplasia tissues [31].
 

Analytical, diagnostic and therapeutic context of Prostatic Hyperplasia

References

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  19. Trans-differentiation of prostatic stromal cells leads to decreased glycoprotein hormone alpha production. Rumpold, H., Mascher, K., Untergasser, G., Plas, E., Hermann, M., Berger, P. J. Clin. Endocrinol. Metab. (2002) [Pubmed]
  20. Interplay between sex steroids and melatonin in regulation of human benign prostate epithelial cell growth. Gilad, E., Matzkin, H., Zisapel, N. J. Clin. Endocrinol. Metab. (1997) [Pubmed]
  21. Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer: potential clinical applications. Guan, M., Zhou, X., Soulitzis, N., Spandidos, D.A., Popescu, N.C. Clin. Cancer Res. (2006) [Pubmed]
  22. The induction of prostatic hypertrophy in the dog with androstanediol. Walsh, P.C., Wilson, J.D. J. Clin. Invest. (1976) [Pubmed]
  23. Gamma-aminobutyric acid as a promoting factor of cancer metastasis; induction of matrix metalloproteinase production is potentially its underlying mechanism. Azuma, H., Inamoto, T., Sakamoto, T., Kiyama, S., Ubai, T., Shinohara, Y., Maemura, K., Tsuji, M., Segawa, N., Masuda, H., Takahara, K., Katsuoka, Y., Watanabe, M. Cancer Res. (2003) [Pubmed]
  24. Restoration of insulin-like growth factor binding protein-related protein 1 has a tumor-suppressive activity through induction of apoptosis in human prostate cancer. Mutaguchi, K., Yasumoto, H., Mita, K., Matsubara, A., Shiina, H., Igawa, M., Dahiya, R., Usui, T. Cancer Res. (2003) [Pubmed]
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  26. Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells. De Marzo, A.M., Meeker, A.K., Epstein, J.I., Coffey, D.S. Am. J. Pathol. (1998) [Pubmed]
  27. A role for estrogen receptor beta in the regulation of growth of the ventral prostate. Weihua, Z., Makela, S., Andersson, L.C., Salmi, S., Saji, S., Webster, J.I., Jensen, E.V., Nilsson, S., Warner, M., Gustafsson, J.A. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  28. Hey1, a mediator of notch signaling, is an androgen receptor corepressor. Belandia, B., Powell, S.M., García-Pedrero, J.M., Walker, M.M., Bevan, C.L., Parker, M.G. Mol. Cell. Biol. (2005) [Pubmed]
  29. Repressors of androgen and progesterone receptor action. Agoulnik, I.U., Krause, W.C., Bingman, W.E., Rahman, H.T., Amrikachi, M., Ayala, G.E., Weigel, N.L. J. Biol. Chem. (2003) [Pubmed]
  30. Monocyte chemoattractant protein-1 gene expression in prostatic hyperplasia and prostate adenocarcinoma. Mazzucchelli, L., Loetscher, P., Kappeler, A., Uguccioni, M., Baggiolini, M., Laissue, J.A., Mueller, C. Am. J. Pathol. (1996) [Pubmed]
  31. Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component. Kondo, Y., Koga, S., Komata, T., Kondo, S. Oncogene (2000) [Pubmed]
  32. Lack of the latent transforming growth factor beta binding protein in malignant, but not benign prostatic tissue. Eklöv, S., Funa, K., Nordgren, H., Olofsson, A., Kanzaki, T., Miyazono, K., Nilsson, S. Cancer Res. (1993) [Pubmed]
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  34. Calcium-binding proteins S100A8 and S100A9 as novel diagnostic markers in human prostate cancer. Hermani, A., Hess, J., De Servi, B., Medunjanin, S., Grobholz, R., Trojan, L., Angel, P., Mayer, D. Clin. Cancer Res. (2005) [Pubmed]
  35. Androgen and glucocorticoid receptors in the stroma and epithelium of prostatic hyperplasia and carcinoma. Mohler, J.L., Chen, Y., Hamil, K., Hall, S.H., Cidlowski, J.A., Wilson, E.M., French, F.S., Sar, M. Clin. Cancer Res. (1996) [Pubmed]
  36. In situ hybridization for gastrin-releasing peptide receptor (GRP receptor) expression in prostatic carcinoma. Bartholdi, M.F., Wu, J.M., Pu, H., Troncoso, P., Eden, P.A., Feldman, R.I. Int. J. Cancer (1998) [Pubmed]
 
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