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Gene Review

FGF16  -  fibroblast growth factor 16

Homo sapiens

Synonyms: FGF-16, Fibroblast growth factor 16, MF4
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Disease relevance of FGF16

  • Although the predicted FGF-16 amino acid sequence lacks a typical signal sequence, recombinant rat FGF-16 was efficiently secreted by Sf9 insect cells infected with recombinant baculovirus containing the cDNA [1].

High impact information on FGF16


Biological context of FGF16


Anatomical context of FGF16


Analytical, diagnostic and therapeutic context of FGF16


  1. Structure and expression of a novel member, FGF-16, on the fibroblast growth factor family. Miyake, A., Konishi, M., Martin, F.H., Hernday, N.A., Ozaki, K., Yamamoto, S., Mikami, T., Arakawa, T., Itoh, N. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
  2. Fibroblast growth factor 16 and 18 are expressed in human cardiovascular tissues and induce on endothelial cells migration but not proliferation. Antoine, M., Wirz, W., Tag, C.G., Gressner, A.M., Wycislo, M., Müller, R., Kiefer, P. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  3. Comparative genomics on FGF16 orthologs. Katoh, Y., Katoh, M. Int. J. Mol. Med. (2005) [Pubmed]
  4. Cloning and bacterial expression of postnatal mouse heart FGF-16. Sontag, D.P., Cattini, P.A. Mol. Cell. Biochem. (2003) [Pubmed]
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