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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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Disease relevance of Pharmacogenetics


Psychiatry related information on Pharmacogenetics


High impact information on Pharmacogenetics


Chemical compound and disease context of Pharmacogenetics


Biological context of Pharmacogenetics


Anatomical context of Pharmacogenetics


Associations of Pharmacogenetics with chemical compounds


Gene context of Pharmacogenetics


Analytical, diagnostic and therapeutic context of Pharmacogenetics


  1. Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome. Camilleri, M., Atanasova, E., Carlson, P.J., Ahmad, U., Kim, H.J., Viramontes, B.E., McKinzie, S., Urrutia, R. Gastroenterology (2002) [Pubmed]
  2. ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach. Ho, G.T., Soranzo, N., Nimmo, E.R., Tenesa, A., Goldstein, D.B., Satsangi, J. Hum. Mol. Genet. (2006) [Pubmed]
  3. Clinical pharmacokinetics of anti-metabolites. Peters, G.J., Schornagel, J.H., Milano, G.A. Cancer Surv. (1993) [Pubmed]
  4. Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer. Ridge, S.A., Sludden, J., Wei, X., Sapone, A., Brown, O., Hardy, S., Canney, P., Fernandez-Salguero, P., Gonzalez, F.J., Cassidy, J., McLeod, H.L. Br. J. Cancer (1998) [Pubmed]
  5. The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis. Warren, R.B., Griffiths, C.E. Br. J. Dermatol. (2005) [Pubmed]
  6. Focus on The 5-HT1A receptor: emerging role of a gene regulatory variant in psychopathology and pharmacogenetics. Lesch, K.P., Gutknecht, L. Int. J. Neuropsychopharmacol. (2004) [Pubmed]
  7. Smoking cessation treatment: pharmacogenetic assessment. Munafò, M.R., Lerman, C., Niaura, R., Shields, A.E., Swan, G.E. Curr. Opin. Mol. Ther. (2005) [Pubmed]
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  9. Autonomic nervous system pharmacogenomics: a progress report. Kirstein, S.L., Insel, P.A. Pharmacol. Rev. (2004) [Pubmed]
  10. Clinical and toxicological relevance of CYP2C9: drug-drug interactions and pharmacogenetics. Rettie, A.E., Jones, J.P. Annu. Rev. Pharmacol. Toxicol. (2005) [Pubmed]
  11. Pharmacogenetics of sulfotransferase. Nagata, K., Yamazoe, Y. Annu. Rev. Pharmacol. Toxicol. (2000) [Pubmed]
  12. Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase. Weinshilboum, R.M., Otterness, D.M., Szumlanski, C.L. Annu. Rev. Pharmacol. Toxicol. (1999) [Pubmed]
  13. Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease. Gearry, R.B., Barclay, M.L. J. Gastroenterol. Hepatol. (2005) [Pubmed]
  14. Methylation pharmacogenetics: thiopurine methyltransferase as a model system. Weinshilboum, R.M. Xenobiotica (1992) [Pubmed]
  15. Human thiopurine S-methyltransferase pharmacogenetics: variant allozyme misfolding and aggresome formation. Wang, L., Nguyen, T.V., McLaughlin, R.W., Sikkink, L.A., Ramirez-Alvarado, M., Weinshilboum, R.M. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  16. Human arsenic methyltransferase (AS3MT) pharmacogenetics: gene resequencing and functional genomics studies. Wood, T.C., Salavagionne, O.E., Mukherjee, B., Wang, L., Klumpp, A.F., Thomae, B.A., Eckloff, B.W., Schaid, D.J., Wieben, E.D., Weinshilboum, R.M. J. Biol. Chem. (2006) [Pubmed]
  17. Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment. Lee, E., Ryan, S., Birmingham, B., Zalikowski, J., March, R., Ambrose, H., Moore, R., Lee, C., Chen, Y., Schneck, D. Clin. Pharmacol. Ther. (2005) [Pubmed]
  18. X-chromosome inactivation patterns and androgen receptor functionality influence phenotype and social characteristics as well as pharmacogenetics of testosterone therapy in Klinefelter patients. Zitzmann, M., Depenbusch, M., Gromoll, J., Nieschlag, E. J. Clin. Endocrinol. Metab. (2004) [Pubmed]
  19. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Weinshilboum, R.M., Sladek, S.L. Am. J. Hum. Genet. (1980) [Pubmed]
  20. Human UGT1A6 pharmacogenetics: identification of a novel SNP, characterization of allele frequencies and functional analysis of recombinant allozymes in human liver tissue and in cultured cells. Nagar, S., Zalatoris, J.J., Blanchard, R.L. Pharmacogenetics (2004) [Pubmed]
  21. Tolbutamide pharmacogenetics and the UGDP controversy. Scott, J., Poffenbarger, P.L. JAMA (1979) [Pubmed]
  22. Application of pharmacogenetics to optimization of mercaptopurine dosing. Balis, F.M., Adamson, P.C. J. Natl. Cancer Inst. (1999) [Pubmed]
  23. In silico pharmacogenetics of warfarin metabolism. Guo, Y., Weller, P., Farrell, E., Cheung, P., Fitch, B., Clark, D., Wu, S.Y., Wang, J., Liao, G., Zhang, Z., Allard, J., Cheng, J., Nguyen, A., Jiang, S., Shafer, S., Usuka, J., Masjedizadeh, M., Peltz, G. Nat. Biotechnol. (2006) [Pubmed]
  24. Arylamine N-acetyltransferases - of mice, men and microorganisms. Upton, A., Johnson, N., Sandy, J., Sim, E. Trends Pharmacol. Sci. (2001) [Pubmed]
  25. Homocysteine, pharmacogenetics, and neurotoxicity in children with leukemia. Kishi, S., Griener, J., Cheng, C., Das, S., Cook, E.H., Pei, D., Hudson, M., Rubnitz, J., Sandlund, J.T., Pui, C.H., Relling, M.V. J. Clin. Oncol. (2003) [Pubmed]
  26. Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. Fellay, J., Marzolini, C., Meaden, E.R., Back, D.J., Buclin, T., Chave, J.P., Decosterd, L.A., Furrer, H., Opravil, M., Pantaleo, G., Retelska, D., Ruiz, L., Schinkel, A.H., Vernazza, P., Eap, C.B., Telenti, A. Lancet (2002) [Pubmed]
  27. CYP3A variation and the evolution of salt-sensitivity variants. Thompson, E.E., Kuttab-Boulos, H., Witonsky, D., Yang, L., Roe, B.A., Di Rienzo, A. Am. J. Hum. Genet. (2004) [Pubmed]
  28. Attention-deficit/hyperactivity disorder pharmacogenomics. McGough, J.J. Biol. Psychiatry (2005) [Pubmed]
  29. Human phenol sulfotransferase pharmacogenetics: STP1 gene cloning and structural characterization. Raftogianis, R.B., Her, C., Weinshilboum, R.M. Pharmacogenetics (1996) [Pubmed]
  30. Pharmacotherapy and pharmacogenetics of nicotine dependence. Berrettini, W.H., Lerman, C.E. The American journal of psychiatry. (2005) [Pubmed]
  31. Evolutionary pharmacogenetics of CYP2D6 in Ngawbe Guaymi of Panama: allele-specific PCR detection of the CYP2D6B allele and RFLP analysis. Jorge, L.F., Arias, T.D., Griese, U., Nebert, D.W., Eichelbaum, M. Pharmacogenetics (1993) [Pubmed]
  32. The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model. Cleary, J., Mikus, G., Somogyi, A., Bochner, F. J. Pharmacol. Exp. Ther. (1994) [Pubmed]
  33. Evolution of the cytochrome P450 superfamily: sequence alignments and pharmacogenetics. Lewis, D.F., Watson, E., Lake, B.G. Mutat. Res. (1998) [Pubmed]
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