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Gene Review

ACY3  -  aspartoacylase (aminocyclase) 3

Homo sapiens

Synonyms: ACY-3, ASPA2, Acylase III, Aminoacylase-3, Aspartoacylase-2, ...
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Disease relevance of ACY3

  • Body weight was not significantly affected by HCBP except during the 4th instar [1].
  • 5. These results suggest that HCBP originates from beta-lipoprotein, and beta-lipoprotein may have an important role in cholesterol accumulation on radicular cysts [2].

High impact information on ACY3


Biological context of ACY3

  • Identifying body residues of HCBP associated with 10-d mortality and partial life cycle effects in the midge, Chironomus riparius [1].

Associations of ACY3 with chemical compounds

  • The relationship between the body residue of 2,2',4,4',5,5'-hexachlorobiphenyl (HCBP) and its effects, including 10-d mortality and chronic sublethal effects on the midge, Chironomus riparius, are examined in a partial life cycle assessment [1].
  • 2. Relationship between the amounts of apo B and free cholesterol or activity of heat-stable cholesterol-binding protein (HCBP) were examined [2].

Analytical, diagnostic and therapeutic context of ACY3


  1. Identifying body residues of HCBP associated with 10-d mortality and partial life cycle effects in the midge, Chironomus riparius. Hwang, H., Fisher, S.W., Landrum, P.F. Aquat. Toxicol. (2001) [Pubmed]
  2. Studies on cholesterol accumulation in radicular cyst fluid--origin of heat-stable cholesterol-binding protein. Yashima, M., Ogura, N., Abiko, Y. Int. J. Biochem. (1990) [Pubmed]
  3. Sediment characteristics affecting desorption kinetics of select PAH and PCB congeners for seven laboratory spiked sediments. Kukkonen, J.V., Landrum, P.F., Mitra, S., Gossiaux, D.C., Gunnarsson, J., Weston, D. Environ. Sci. Technol. (2003) [Pubmed]
  4. The contrasting roles of sedimentary plant-derived carbon and black carbon on sediment-spiked hydrophobic organic contaminant bioavailability to Diporeia species and Lumbriculus variegatus. Kukkonen, J.V., Mitra, S., Landrum, P.F., Gossiaux, D.C., Gunnarsson, J., Weston, D. Environ. Toxicol. Chem. (2005) [Pubmed]
  5. Toxicokinetics of organic contaminants in Hyalella azteca. Nuutinen, S., Landrum, P.F., Schuler, L.J., Kukkonen, J.V., Lydy, M.J. Arch. Environ. Contam. Toxicol. (2003) [Pubmed]
  6. System-level responses of lake ecosystems to chemical stresses using exergy and structural exergy as ecological indicators. Xu, F.L., Dawson, R.W., Tao, S., Li, B.G., Cao, J. Chemosphere (2002) [Pubmed]
  7. Carcinoembryonic antigen-binding immunoglobulin isolated from normal human serum by affinity chromatography. Pressman, D., Chu, T.M., Grossberg, A.L. J. Natl. Cancer Inst. (1979) [Pubmed]
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