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Gene Review

TCRVsSgp2  -  nucleoprotein

Tacaribe virus

 
 
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Disease relevance of TCRVsSgp2

 

High impact information on TCRVsSgp2

 

Anatomical context of TCRVsSgp2

 

Analytical, diagnostic and therapeutic context of TCRVsSgp2

  • Components of 48,000, 38,000, and 28,000 daltons, when analyzed by two-dimensional tryptic peptide mapping, were found to be derived from NP [7].
  • By Western blotting, the 64 kDa protein bound a JV neutralizing antibody and was considered to be the viral nucleoprotein [8].

References

  1. Resistance to superinfection of Vero cells persistently infected with Junin virus. Ellenberg, P., Edreira, M., Scolaro, L. Arch. Virol. (2004) [Pubmed]
  2. The nucleoprotein of Pichinde virus expressed by a vaccinia-Pichinde virus recombinant partially protects hamsters from lethal virus challenge. Ozols, D.Y., Rawls, W.E., Rosenthal, K.L., Harnish, D.G. Arch. Virol. (1994) [Pubmed]
  3. Tacaribe virus Z protein interacts with the L polymerase protein to inhibit viral RNA synthesis. Jácamo, R., López, N., Wilda, M., Franze-Fernández, M.T. J. Virol. (2003) [Pubmed]
  4. Polarized entry and release of Junin virus, a New World arenavirus. Cordo, S.M., Cesio y Acuña, M., Candurra, N.A. J. Gen. Virol. (2005) [Pubmed]
  5. Establishment of conventional and fluorescence resonance energy transfer-based real-time PCR assays for detection of pathogenic New World arenaviruses. Vieth, S., Drosten, C., Charrel, R., Feldmann, H., Günther, S. J. Clin. Virol. (2005) [Pubmed]
  6. Involvement of the cytoskeleton in Junin virus multiplication. Candurra, N.A., Lago, M.J., Maskin, L., Damonte, E.B. J. Gen. Virol. (1999) [Pubmed]
  7. Characterization of polypeptides immunoprecipitable from Pichinde virus-infected BHK-21 cells. Harnish, D.G., Leung, W.C., Rawls, W.E. J. Virol. (1981) [Pubmed]
  8. Molecular characteristics of Junin virus. Bushar, G., Sagripanti, J.L. J. Virol. Methods (1997) [Pubmed]
 
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