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Gene Review

SNX17  -  sorting nexin 17

Homo sapiens

Synonyms: KIAA0064, Sorting nexin-17
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High impact information on SNX17


Biological context of SNX17


Anatomical context of SNX17


Associations of SNX17 with chemical compounds


Physical interactions of SNX17


Other interactions of SNX17

  • The interaction was also detected in HEK 293 cells transiently expressing GFP-tagged KRIT1 and Xpress-tagged SNX17 [6].


  1. Sorting nexin 17 facilitates LRP recycling in the early endosome. van Kerkhof, P., Lee, J., McCormick, L., Tetrault, E., Lu, W., Schoenfish, M., Oorschot, V., Strous, G.J., Klumperman, J., Bu, G. EMBO J. (2005) [Pubmed]
  2. The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor. Stockinger, W., Sailler, B., Strasser, V., Recheis, B., Fasching, D., Kahr, L., Schneider, W.J., Nimpf, J. EMBO J. (2002) [Pubmed]
  3. Sorting motifs in the intracellular domain of the low density lipoprotein receptor interact with a novel domain of sorting nexin-17. Burden, J.J., Sun, X.M., García, A.B., Soutar, A.K. J. Biol. Chem. (2004) [Pubmed]
  4. Sorting nexin 17 accelerates internalization yet retards degradation of P-selectin. Williams, R., Schlüter, T., Roberts, M.S., Knauth, P., Bohnensack, R., Cutler, D.F. Mol. Biol. Cell (2004) [Pubmed]
  5. Functions of sorting nexin 17 domains and recognition motif for P-selectin trafficking. Knauth, P., Schlüter, T., Czubayko, M., Kirsch, C., Florian, V., Schreckenberger, S., Hahn, H., Bohnensack, R. J. Mol. Biol. (2005) [Pubmed]
  6. Sorting nexin 17, a non-self-assembling and a PtdIns(3)P high class affinity protein, interacts with the cerebral cavernous malformation related protein KRIT1. Czubayko, M., Knauth, P., Schlüter, T., Florian, V., Bohnensack, R. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  7. A new member of the sorting nexin family interacts with the C-terminus of P-selectin. Florian, V., Schlüter, T., Bohnensack, R. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
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