Disease relevance of Maximal Voluntary Ventilation

• Respiratory muscle strength and endurance were evaluated by maximal inspiratory and expiratory pressures (MIP and MEP, respectively) and the maximal duration that isocapnic hyperventilation equal to 50 and 70% of the 12-s maximal voluntary ventilation could be sustained (DSV) [1].

High impact information on Maximal Voluntary Ventilation

• Pulmonary function studies revealed a severe restrictive abnormality with a low maximal inspiratory pressure and maximal voluntary ventilation [2].
• The breathing reserve index (BRI = minute ventilation/maximal voluntary ventilation) at the lactate threshold (LT) is a predictor of a pulmonary mechanical limit to incremental exercise [3].
• Blood lactate concentrations were measured in five patients with chronic airways obstruction after 10 minutes' sustained maximal voluntary ventilation (SMVV) with end-tidal carbon dioxide tension kept constant and after a 12-minute walk [4].
• The WR correlated negatively with the vital capacity/predicted value ratio, correlated negatively with the maximal voluntary ventilation volume/predicted value ratio, and correlated positively with the residual volume/total lung capacity ratio in the COPD group [5].
• The cyclists reached an average maximal O2 consumption of 72 ml. kg-1. min-1 (range: 67-82 ml. kg-1. min-1) and ventilation of 147 l/min (range: 122-180 l/min) (88% of preexercise maximal voluntary ventilation in 15 s) [6].

Biological context of Maximal Voluntary Ventilation

• However, in the erythropoietin group, the diffusing capacity, maximal voluntary ventilation, forced vital capacity and peak expiratory flow rate values increased significantly [7].
• Measures were: pulmonary volumes; arterial blood gases; maximal voluntary ventilation (MVV); maximal inspiratory and expiratory pressures (MIP and MEP, respectively); and breathing patterns ventilation (VE), tidal volume (VT), and respiratory frequency (Rf) [8].
• Four to six subjects performed maximal voluntary ventilation (MVV) and forced expirations during rest, exercise (50, 125, and 200 W), and inhalation of air and CO2 and air at rest while submerged at pressures of 1.45, 2.82, 4.64, and 6.76 atm [9].

Anatomical context of Maximal Voluntary Ventilation

• The strength of the respiratory muscles can be evaluated from static measurements (maximal inspiratory and expiratory pressures, MIP and MEP) or inferred from dynamic maneuvers (maximal voluntary ventilation, MVV) [10].

Associations of Maximal Voluntary Ventilation with chemical compounds

• MA had a significantly lower ventilatory response to submaximal exercise at the same O2 uptake (VE/VO2) and greater maximal voluntary ventilation (MVV), maximal exercise ventilation (VEmax), and ratio of VEmax to MVV than CON [11].
• Mean VC was higher and FEV1/VC was lower in group 2, but mean FEV1, maximal voluntary ventilation, and diffusing capacity for carbon monoxide were not different [12].
• Maximal static inspiratory (Pi) and expiratory (Pe) pressures, maximal voluntary ventilation (MVV), blood lactate (LAC), arterialized blood gases (ABG), plasma glucose (GLU), and, with a visual analog scale, subjective tiredness were assessed [13].
• Performance was evaluated during 1-min maximal voluntary ventilation (1-min MVV) test, during 7-min 7% CO2 breathing and during quiet breathing [14].
• Six hours before each of the following challenges 10 mg montelukast or placebo was ingested: (a) a six minute, cold air (-3 degrees C) maximal effort work accumulation cycle ergometer exercise; (b) EVH, breathing 5% CO(2) compressed air at 85% maximal voluntary ventilation for six minutes [15].

Gene context of Maximal Voluntary Ventilation

• In severe COPD, ventilation at peak exercise may exceed the resting maximal voluntary ventilation (MVV) [16].

References