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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Sensation Disorders

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Disease relevance of Sensation Disorders


High impact information on Sensation Disorders


Chemical compound and disease context of Sensation Disorders

  • We investigated whether sensory disorders in rats were related to glucose metabolism by aldose reductase [4].
  • We characterized prostaglandin E receptor subtypes (EP1-3) involved in these sensory disorders by use of 7 synthetic prostanoid analogues [7].
  • The possible mechanisms responsible for the conversion of the high threshold phasic flexor reflex into a low threshold tonic reflex are discussed as are the possible implications for sensory disorders that accompany chronic injury in man [8].
  • Based on this observation we attempted to develop an hypothesis of the possible role vitamin E might play in these sensory disorders [9].
  • This suggests, by inference, a crucial contribution of the NMDA-induced increased excitability to the expression of neuronal sensitization related to this painful sensory disorder [10].

Gene context of Sensation Disorders

  • RHDP performed defectively whether they had closed or open eyes, which tends to indicate a perceptual multimodal integration disorder rather than a modality-related sensory disorder [11].


  1. Degenerative vascular changes in children with diabetes mellitus. Karahanyan, E., Boikinov, B., Pechilkova, M., Grozeva, D., Mantarkova, Z., Chalakova, N., Teodosieva, E., Ivanov, I. Folia medica. (1994) [Pubmed]
  2. Is dystonia a sensory disorder? Hallett, M. Ann. Neurol. (1995) [Pubmed]
  3. Molecular determinants of vanilloid sensitivity in TRPV1. Gavva, N.R., Klionsky, L., Qu, Y., Shi, L., Tamir, R., Edenson, S., Zhang, T.J., Viswanadhan, V.N., Toth, A., Pearce, L.V., Vanderah, T.W., Porreca, F., Blumberg, P.M., Lile, J., Sun, Y., Wild, K., Louis, J.C., Treanor, J.J. J. Biol. Chem. (2004) [Pubmed]
  4. Prevention of sensory disorders in diabetic Sprague-Dawley rats by aldose reductase inhibition or treatment with ciliary neurotrophic factor. Calcutt, N.A., Freshwater, J.D., Mizisin, A.P. Diabetologia (2004) [Pubmed]
  5. Lidocaine test in neuralgia. Marchettini, P., Lacerenza, M., Marangoni, C., Pellegata, G., Sotgiu, M.L., Smirne, S. Pain (1992) [Pubmed]
  6. Blockade by ONO-NT-012, a unique prostanoid analogue, of prostaglandin E2-induced allodynia in conscious mice. Minami, T., Nishihara, I., Sakamoto, K., Ito, S., Hyodo, M., Hayaishi, O. Br. J. Pharmacol. (1995) [Pubmed]
  7. Characterization of EP-receptor subtypes involved in allodynia and hyperalgesia induced by intrathecal administration of prostaglandin E2 to mice. Minami, T., Nishihara, I., Uda, R., Ito, S., Hyodo, M., Hayaishi, O. Br. J. Pharmacol. (1994) [Pubmed]
  8. Injury-induced plasticity of the flexor reflex in chronic decerebrate rats. Woolf, C.J., McMahon, S.B. Neuroscience (1985) [Pubmed]
  9. Deficient dietary intake of vitamin E in patients with taste and smell dysfunctions: is vitamin E a cofactor in taste bud and olfactory epithelium apoptosis and in stem cell maturation and development? Henkin, R.I., Hoetker, J.D. Nutrition (Burbank, Los Angeles County, Calif.) (2003) [Pubmed]
  10. NMDA and strychnine diversely modulate spinal dorsal horn noxious responsiveness in normal rats: potential significance to sensory disorders in neuropathic pain. Sotgiu, M.L., Biella, G.E. Somatosensory & motor research. (2002) [Pubmed]
  11. Defective reproduction of passive meaningless gestures in right brain damage: a perceptual disorder of one's own body knowledge? Borde, C., Mazaux, J.M., Barat, M. Cortex; a journal devoted to the study of the nervous system and behavior. (2006) [Pubmed]
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