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MeSH Review

Prince Edward Island

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Disease relevance of Prince Edward Island

  • Seroepidemiology of Q fever in Nova Scotia and Prince Edward Island [1].
  • This study investigates the potential impact of groundwater nitrate exposure on prematurity and intrauterine growth restriction on Prince Edward Island. A total of 210 intrauterine growth restriction cases, 336 premature births, and 4098 controls were abstracted from a database of all Island births [2].
  • SETTING: The only tertiary care centre for children's heart disease in the provinces of Nova Scotia, New Brunswick and Prince Edward Island, areas of relative geographic isolation (combined population of 1.75 million people) [3].
  • The prevalence of Coxiella burnetti infection (Q fever) was determined among Nova Scotia (N.S.) and Prince Edward Island (P.E.I.) blood donors by using the complement fixation and microimmunofluorescence (IF) test [1].
  • Forty human isolates and twenty-eight animal isolates of Pseudomonas aeruginosa from Prince Edward Island area (Atlantic Canada) were serotyped using a kit consisting of 4 polyvalent O-group antisera and 17 monovalent O-type (serovar) antisera, in accordance with the International Antigenic Typing Scheme [4].

High impact information on Prince Edward Island

  • Mussels associated with this illness were traced to cultivation beds in three river estuaries on the eastern coast of Prince Edward Island. Domoic acid, which can act as an excitatory neurotransmitter, was identified in mussels left uneaten by the patients and in mussels sampled from these estuaries [5].
  • Sera were collected from 238 high-school students in Prince Edward Island for the determination of immune status before an anticipated measles outbreak [6].
  • SETTING: The Canadian provinces of Nova Scotia, New Brunswick, Newfoundland and Labrador, and Prince Edward Island in 1998 [7].
  • A family has been identified in the Canadian province of Prince Edward Island in which 2 sisters have systemic lupus erythematosus in a sibship of 14 [8].
  • Objectives of this study were to determine which land use practices were spatially associated with ground water nitrate concentrations across Prince Edward Island (PEI), Canada, and which spatial aggregation is the preferred unit of analyses [9].

Associations of Prince Edward Island with chemical compounds

  • Levels and determinants of formaldehyde, acetaldehyde, and acrolein in residential indoor air in Prince Edward Island, Canada [10].
  • Domoic acid, a structural analogue of kainic acid, has been identified as the toxin that poisoned people who consumed contaminated blue mussels harvested from eastern Prince Edward Island in December of 1987 [11].
  • The effect of non-nutritional factors on milk urea nitrogen levels in dairy cows in Prince Edward Island, Canada [12].
  • Consumption of cultivated blue mussels from Prince Edward Island was recently associated with episodes of gastro-intestinal and neurological distress [13].
  • A total of 1317 Holstein cows from 45 farms in the Canadian provinces of Quebec, Prince Edward Island (PEI) and Ontario were enrolled in a randomized trial during 1998 and 1999 to further confirm the efficacy of a monensin controlled release capsule in preventing periparturient disease in lactating dairy cows [14].

Gene context of Prince Edward Island

  • Using a modified DSP extraction procedure the quantities of free fatty acids determined (by latroscan TLC/FID) in the hepatopancreases of mussels were 2.9 mg/g (Ship Harbour 1), 2.2 mg/g (Ship Harbour 2), 1.2 mg/g (Wine Harbour), and 0.15 mg/g (Prince Edward Island, control) [15].
  • OBJECTIVES: Firstly, to determine the accuracy of the Radiometer ABL 625 lactate electrode (Radiometer Medical Pty Ltd, Nunawading, Victoria, Australia) by comparing the lactate values obtained by this method to those obtained with the Hitachi 917 lactate analyser (Boehringer Mannheim Corporation, Charlottetown, Prince Edward Island, Canada) [16].


  1. Seroepidemiology of Q fever in Nova Scotia and Prince Edward Island. Marrie, T.J., Van Buren, J., Faulkner, R.S., Haldane, E.V., Williams, J.C., Kwan, C. Can. J. Microbiol. (1984) [Pubmed]
  2. Agricultural contamination of groundwater as a possible risk factor for growth restriction or prematurity. Bukowski, J., Somers, G., Bryanton, J. J. Occup. Environ. Med. (2001) [Pubmed]
  3. Trends in the prevalence of congenital heart disease: comprehensive observations over a 24-year period in a defined region of Canada. Roy, D.L., McIntyre, L., Human, D.G., Nanton, M.A., Sherman, G.J., Allen, L.M., Finley, J.P. The Canadian journal of cardiology. (1994) [Pubmed]
  4. Serotypes of Pseudomonas aeruginosa from human and animal sources. Hariharan, H., McNair, N., Bryenton, J., St Onge, J., Ojo, M., Long, R. Zentralbl. Bakteriol. (1989) [Pubmed]
  5. An outbreak of toxic encephalopathy caused by eating mussels contaminated with domoic acid. Perl, T.M., Bédard, L., Kosatsky, T., Hockin, J.C., Todd, E.C., Remis, R.S. N. Engl. J. Med. (1990) [Pubmed]
  6. Comparison of measles antihemolysin test, enzyme-linked immunosorbent assay, and hemagglutination inhibition test with neutralization test for determination of immune status. Neumann, P.W., Weber, J.M., Jessamine, A.G., O'Shaughnessy, M.V. J. Clin. Microbiol. (1985) [Pubmed]
  7. The association between substance use, unplanned sexual intercourse and other sexual behaviours among adolescent students. Poulin, C., Graham, L. Addiction (2001) [Pubmed]
  8. Familial systemic lupus erythematosus: evidence for separate loci controlling C4 deficiency and formation of antibodies to DNA, nRNP, Ro and La. Verrier Jones, J., Jones, E., Forsyth, S.J., Skanes, V.M., Reichlin, M., MacSween, J.M., Eastwood, S., Carr, R.I. J. Rheumatol. (1987) [Pubmed]
  9. Spatial analysis of land use impact on ground water nitrate concentrations. Benson, V.S., VanLeeuwen, J.A., Sanchez, J., Dohoo, I.R., Somers, G.H. J. Environ. Qual. (2006) [Pubmed]
  10. Levels and determinants of formaldehyde, acetaldehyde, and acrolein in residential indoor air in Prince Edward Island, Canada. Gilbert, N.L., Guay, M., David Miller, J., Judek, S., Chan, C.C., Dales, R.E. Environmental research. (2005) [Pubmed]
  11. Pharmacology of systemically administered domoic acid in mice. Tasker, R.A., Connell, B.J., Strain, S.M. Can. J. Physiol. Pharmacol. (1991) [Pubmed]
  12. The effect of non-nutritional factors on milk urea nitrogen levels in dairy cows in Prince Edward Island, Canada. Arunvipas, P., Dohoo, I.R., VanLeeuwen, J.A., Keefe, G.P. Prev. Vet. Med. (2003) [Pubmed]
  13. Domoic acid poisoning and mussel-associated intoxication: preliminary investigations into the response of mice and rats to toxic mussel extract. Iverson, F., Truelove, J., Nera, E., Tryphonas, L., Campbell, J., Lok, E. Food Chem. Toxicol. (1989) [Pubmed]
  14. Prepartum monensin for the reduction of energy associated disease in postpartum dairy cows. Duffield, T., Bagg, R., DesCoteaux, L., Bouchard, E., Brodeur, M., DuTremblay, D., Keefe, G., LeBlanc, S., Dick, P. J. Dairy Sci. (2002) [Pubmed]
  15. An incident of elevated levels of unsaturated free fatty acids in mussels from Nova Scotia and their toxic effect in mice after intraperitoneal injection. Lawrence, J.F., Chadha, R.K., Ratnayake, W.M., Truelove, J.F. Nat. Toxins (1994) [Pubmed]
  16. Umbilical cord blood lactate in normal infants: comparison between two methods of measurement. Sinn, J.K., Lloyd, J., Todd, D.A., Lazarus, R., Maesel, A., John, E. Journal of paediatrics and child health. (2001) [Pubmed]
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