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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Leg Bones

 
 
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High impact information on Leg Bones

  • The vitamin B-6 antimetabolite 4-deoxypyridoxine, when injected into 13-day chick embryos, has the effect of increasing the amount of collagen solubilized from the leg bones by buffered saline solutions, 24 h after the injection [1].
  • The soleus, a slow muscle composed predominantly of type I fibers, expresses low ATPase activity and contains much lower levels of ski mRNA. mRNA from the ski transgene is also expressed at high levels in the osteocytes of the leg bones of 15-day and older transgenic mice [2].
  • METHODS: BMCs were isolated from minipig leg bones, treated with 5-azacytidine (10 microM) for 24 h, cultured for 7 days and labeled with a fluoroscopic dye (DIL) [3].
  • Microbial phytase in finisher diets of White Pekin ducks: effects on growth performance, plasma phosphorus concentration, and leg bone characteristics [4].
  • Leg bone pain syndrome due to cyclosporine in a renal transplant patient [5].
 

Anatomical context of Leg Bones

  • By 18 h, the accumulation maxima in the major tissues were: leg bones, 20% for Ga+3 (67Ga label) in estradiol-treated males; liver, 51% for Al+3 (26Al label) in control males; kidneys, 32% for In+3 (114mIn label) in estradiol-treated males; and growing oocytes plus ova, 37% for In [6].
 

Associations of Leg Bones with chemical compounds

  • Dual energy gadolinium-153 photonabsorptiometry was used to measure distal leg bone loss at a skeletal segment distant from the fracture to exclude callus formation [7].
  • Among leg bones examined, femur strength was improved by 16% in birds fed 2,000 ppm of ascorbic acid (Experiment 2) [8].
 

Gene context of Leg Bones

  • In an attempt to increase the relative amount of leg bone, a subline (FL) was developed by mass selection for increased shank width at 16 weeks of age from a long-term growth-selected line of turkeys (F) [9].
 

Analytical, diagnostic and therapeutic context of Leg Bones

References

  1. The effect of a vitamin B-6 antagonist, 4-deoxypyridoxine, on the cross-linking of collagen in the developing chick embryo. Bird, T.A., Levene, C.I. Biochem. J. (1983) [Pubmed]
  2. Selective expression of a ski transgene affects IIb fast muscles and skeletal structure. Lana, D.P., Leferovich, J.M., Kelly, A.M., Hughes, S.H. Dev. Dyn. (1996) [Pubmed]
  3. Morphological, electrophysiological and coupling characteristics of bone marrow-derived mononuclear cells-an in vitro-model. Rastan, A.J., Walther, T., Kostelka, M., Garbade, J., Schubert, A., Stein, A., Dhein, S., Mohr, F.W. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. (2005) [Pubmed]
  4. Microbial phytase in finisher diets of White Pekin ducks: effects on growth performance, plasma phosphorus concentration, and leg bone characteristics. Orban, J.I., Adeola, O., Stroshine, R. Poult. Sci. (1999) [Pubmed]
  5. Leg bone pain syndrome due to cyclosporine in a renal transplant patient. Naredo Sánchez, E., Balsa Criado, A., Sanz Guajardo, A., Pantoja Zarza, L., Martín Mola, E., Gijón Baños, J. Clinical and experimental rheumatology. (1994) [Pubmed]
  6. Accumulation and distribution of ions of group-IIIA elements in the tissues and eggs of the Japanese quail. Robinson, G.A., Wasnidge, D.C., Floto, F. Poult. Sci. (1990) [Pubmed]
  7. Quantification by dual photonabsorptiometry of local bone loss after fracture. Ulivieri, F.M., Bossi, E., Azzoni, R., Ronzani, C., Trevisan, C., Montesano, A., Ortolani, S. Clin. Orthop. Relat. Res. (1990) [Pubmed]
  8. Influence of large doses of ascorbic acid on performance, plasma calcium, bone characteristics, and eggshell quality in broilers and Leghorn hens. Orban, J.I., Roland, D.A., Cummins, K., Lovell, R.T. Poult. Sci. (1993) [Pubmed]
  9. The influence of genetic increases in shank width on body weight, walking ability, and reproduction of turkeys. Nestor, K.E., Bacon, W.L., Saif, Y.M., Renner, P.A. Poult. Sci. (1985) [Pubmed]
  10. Effects of castration, with and without testosterone replacement, on leg bone integrity in the domestic fowl. Johnson, A.L., Rendano, V.T. Am. J. Vet. Res. (1984) [Pubmed]
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