High impact information on Entomophthorales

• Transmission electron microscopy showed severe morphological alteration of Basidiobolus sp. exposed to 0.78 micrograms of ketoconazole per ml [1].
• In general, however, Basidiobolus spp. displayed low MICs of fluconazole, itraconazole, ketoconazole and miconazole, and Conidiobolus spp. were resistant to all antifungals tested [2].
• Purification and characterization of the single-strand-specific and guanylic-acid-preferential deoxyribonuclease activity of the extracellular nuclease from Basidiobolus haptosporus [3].
• An extracellular nuclease from Basidiobolus haptosporus (designated as nuclease Bh1) was purified to homogeneity by ammonium sulfate precipitation, heat treatment, negative adsorption on DEAE-cellulose, and chromatography on phenyl-Sepharose followed by FPLC on phenyl-Superose [3].
• Although the Entomophthorales would be expected to be more primitive than the above orders based on the predominance of C28 delta 5, it is not apparent from these data that members of the Zygomycota with ergosterol or its precursors as major sterols evolved from this taxon or the Chytridiomycota [4].

Biological context of Entomophthorales

• Unsaturated ketones (4 and 10) and epoxides (2-3 and 8-9) were the main products of biotransformation performed by means of Zoophthora (Neopandora) phyllobii [5].

Anatomical context of Entomophthorales

• We have found an increase of glucosamine content in purified cell walls of Basidiobolus ranarum grown in presence of Rylux BSU in SGA [6].
• A concomitant but transient occurrence of large numbers of double-membraned vesicles with immature, culturally induced microbodies was demonstrated in thin sections of Basidiobolus haptosporus soon after transfer of the fungus to a defined medium containing xanthine or its catabolites as the sole source of nitrogen [7].

Associations of Entomophthorales with chemical compounds

• Rhizoferrin: a complexone type siderophore of the Mucorales and entomophthorales (Zygomycetes) [8].
• BACKGROUND: Basidiobolomycosis is a rare chronic subcutaneous infection caused by Basidiobolus ranarum, which is usually treated with potassium iodide [9].
• The ability of Basidiobolus species to assimilate xanthine and its catabolites might explain their ecological association with the gut and cloacal contents of various amphibia, reptiles and fish [10].

Gene context of Entomophthorales

• ISSR, ERIC (Enterobacterial Repetitive Intergenic Consensus) and RAPD PCR-based DNA fingerprint analyses were undertaken to study intra-specific variation amongst 30 isolates of P. neoaphidis worldwide, together with six closely related species of Entomophthorales [11].
• Extracellular lipase and proteinase of Basidiobolus haptosporus: possible role in subcutaneous mycosis [12].

References