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MeSH Review

DNA Fingerprinting

 
 
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Disease relevance of DNA Fingerprinting

 

High impact information on DNA Fingerprinting

 

Chemical compound and disease context of DNA Fingerprinting

 

Biological context of DNA Fingerprinting

 

Anatomical context of DNA Fingerprinting

 

Associations of DNA Fingerprinting with chemical compounds

 

Gene context of DNA Fingerprinting

  • Among the 75 mismatched pairs, DNA typing of 63 pairs showed that 51 were mismatched at 1 HLA locus (18 HLA-A, 11 HLA-B, 22 HLA-DRB1) and 12 were mismatched at 2 or more loci [31].
  • Cytogenetics, DNA profiling, expression of basal, luminal, and neuroendocrine differentiation markers, and mutation analyses of the TP53 and androgen receptor (AR) genes were performed [32].
  • Rapid DNA typing for HLA-C using sequence-specific primers (PCR-SSP): identification of serological and non-serologically defined HLA-C alleles including several new alleles [33].
  • In conclusion, LR-HR-PCR-SSP typing is a fast and reliable typing technique for routine DNA typing purposes which gives complete DRB1 subtyping within 4.5 h [34].
  • Thus, PCR-RFLP seems to be one of the best DNA typing methods: it represents direct, accurate, fast, and nonradioactive typing for both HLA-DPA1 and HLA-DPB1 alleles [35].
 

Analytical, diagnostic and therapeutic context of DNA Fingerprinting

  • Sperm DNA typing using allele-specific PCR primers to selectively amplify recombinant TAP2 molecules revealed a highly localized meiotic crossover hotspot approximately 1.2 kb long, unusually abundant in sequence polymorphisms and flanked by DNA much less active in recombination [36].
  • These small cells are presumably of donor origin based on DNA fingerprinting analysis and based on fluorescence in situ hybridization for the Y chromosome in a sex-mismatched case [37].
  • Multivariate analysis revealed the following unfavorable factors: transplantation more than 3 years after diagnosis (relative risk [RR], 1.86; P =.02), patients older than 20 years (RR, 2.27; P =.03), preconditioning regimen without antithymocyte globulin (RR 2.28; P =.04), and HLA-A or -B locus mismatching as determined by DNA typing [31].
  • Forensic DNA typing by capillary electrophoresis using the ABI Prism 310 and 3100 genetic analyzers for STR analysis [38].
  • By a combination of DNA typing and isoelectric focusing of the C7 appearing after transfusion, it was demonstrated that the patient was heterozygous for combined subtotal C6/C7 deficiency (inherited from his father) and a different, so far uncharacterized, subtotal C7 deficiency (inherited from his mother) [39].

References

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  3. Patients with Graves' disease who developed insulin autoimmune syndrome (Hirata disease) possess HLA-Bw62/Cw4/DR4 carrying DRB1*0406. Uchigata, Y., Kuwata, S., Tsushima, T., Tokunaga, K., Miyamoto, M., Tsuchikawa, K., Hirata, Y., Juji, T., Omori, Y. J. Clin. Endocrinol. Metab. (1993) [Pubmed]
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  18. Chimerism of metanephric adenoma but not of carcinoma in kidney transplants. Mengel, M., Jonigk, D., Wilkens, L., Radermacher, J., von Wasielewski, R., Lehmann, U., Haller, H., Mihatsch, M., Kreipe, H. Am. J. Pathol. (2004) [Pubmed]
  19. Analysis of multigene families by DNA fingerprinting of conserved domains: directed cloning of tissue-specific protein tyrosine phosphatases. Boehm, T. Oncogene (1993) [Pubmed]
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  22. Unrelated donor cord blood transplantation in adults with chronic myelogenous leukemia: results in nine patients from a single institution. Sanz, G.F., Saavedra, S., Jiménez, C., Senent, L., Cervera, J., Planelles, D., Bolufer, P., Larrea, L., Martín, G., Martínez, J., Jarque, I., Moscardó, F., Plumé, G., Andreu, R., de la Rubia, J., Barragán, E., Solves, P., Soler, M.A., Sanz, M.A. Bone Marrow Transplant. (2001) [Pubmed]
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  24. Changes in DNA induced by toxic agents. Sawaguchi, T., Wang, X., Sawaguchi, A. Forensic Sci. Int. (1996) [Pubmed]
  25. Mycobacterium tuberculosis transmission among high school students in Greece. Hadjichristodoulou, C., Vasilogiannakopoulos, A., Spala, G., Mavrou, I., Kolonia, V., Marinis, E., Syriopoulou, V., Theodoridou, M. Pediatrics international : official journal of the Japan Pediatric Society. (2005) [Pubmed]
  26. The poly (purine) poly (pyrimidine) sequence in the 5' end of the thyroglobulin gene used as a probe, identifies a DNA fingerprint in man. Gérard, C., Christophe, D., Compère, T., Vassart, G. Nucleic Acids Res. (1990) [Pubmed]
  27. Spoligologos: a bioinformatic approach to displaying and analyzing Mycobacterium tuberculosis data. Driscoll, J.R., Bifani, P.J., Mathema, B., McGarry, M.A., Zickas, G.M., Kreiswirth, B.N., Taber, H.W. Emerging Infect. Dis. (2002) [Pubmed]
  28. Temperature and pH studies of short tandem repeat systems using capillary electrophoresis at elevated pH. Nock, T., Dove, J., McCord, B., Mao, D. Electrophoresis (2001) [Pubmed]
  29. Emergence of a pneumococcal clone with cephalosporin resistance and penicillin susceptibility. Smith, A.M., Botha, R.F., Koornhof, H.J., Klugman, K.P. Antimicrob. Agents Chemother. (2001) [Pubmed]
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  31. Outcome of 154 patients with severe aplastic anemia who received transplants from unrelated donors: the Japan Marrow Donor Program. Kojima, S., Matsuyama, T., Kato, S., Kigasawa, H., Kobayashi, R., Kikuta, A., Sakamaki, H., Ikuta, K., Tsuchida, M., Hoshi, Y., Morishima, Y., Kodera, Y. Blood (2002) [Pubmed]
  32. Molecular characterization of human prostate carcinoma cell lines. van Bokhoven, A., Varella-Garcia, M., Korch, C., Johannes, W.U., Smith, E.E., Miller, H.L., Nordeen, S.K., Miller, G.J., Lucia, M.S. Prostate (2003) [Pubmed]
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  38. Forensic DNA typing by capillary electrophoresis using the ABI Prism 310 and 3100 genetic analyzers for STR analysis. Butler, J.M., Buel, E., Crivellente, F., McCord, B.R. Electrophoresis (2004) [Pubmed]
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