Disease relevance of Brain Stem Infarctions

• Coma was secondary to cardiac arrest in two cases and to brainstem infarction in one [1].
• Cerebrospinal fluid (CSF) homovanillic acid (HVA) concentration was measured in 39 consecutive cases of hemispheric infarction, 7 cases of brainstem infarction, and in 16 controls [2].
• A young woman with CF who had mild pulmonary involvement and who was in good health developed a fulminant illness presenting as brainstem infarction and simulating thrombotic thrombocytopenic purpura [3].
• Despite combined administration of amphotericin-B and 5-FC, she became comatose from brainstem infarction and finally, suddenly died [4].

High impact information on Brain Stem Infarctions

• Mefenamic acid overdose mimicking brainstem stroke [5].
• Even using diffusion-weighted images (DWI) detection of acute brainstem infarction (BI) is still a challenge [6].
• Effects of cerebrovascular autoregulation and CO2 reactivity in experimental localized brainstem infarction [7].
• This case suggests a potential role for clonidine in the treatment of spasticity resulting from brainstem infarction [8].
• In contrast the patients with brainstem infarction increased NA urinary excretion after the manoeuvre, suggesting activation instead of deactivation of the sympathetic nervous system (SNS) [9].

Chemical compound and disease context of Brain Stem Infarctions

• Diaschisis and acetazolamide reactivity in brainstem infarction [10].
• The 2,3,5 triphenyltetrazolium chloride stained sections showed similar volumes of brainstem infarction in both groups (38.3 +/- 9.2 mm3 vs. 34.3 +/- 8.7 mm3, respectively; p > 0.05) [11].
• We report a case of brainstem infarction resulting in apneustic breathing, which was alleviated with buspirone [12].

Gene context of Brain Stem Infarctions

• A 36 year old patient with a brainstem stroke of unknown origin and a secundum atrial septal defect in combination with a persisting prominent eustachian valve is reported [13].
• The other patient was given intra-arterial SK 12 days after an apparently completed brainstem stroke: the therapy failed to cause reperfusion of a vertebral occlusion or produce any clinical improvement [14].

References