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Gene Review

ASD1  -  atrial septal defect 1

Homo sapiens

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Disease relevance of ASD1


Psychiatry related information on ASD1


High impact information on ASD1


Chemical compound and disease context of ASD1


Biological context of ASD1


Anatomical context of ASD1


Associations of ASD1 with chemical compounds

  • In patients with chronic AR who had no clinical signs of cardiac failure, the myocardial content of NE (p less than 0.025), NM (p less than 0.05) and E (p less than 0.05) was significantly reduced compared with that in patients with ASD [25].
  • Before, and 30 min after ASD closure, exhaled NO and plasma nitrate concentration were measured by chemiluminescence (NOA 280, Sievers, Boulder, Colorado) [26].
  • The device, made of a Nitinol and polyester fabric mesh, provides a different approach to defect occlusion by stenting the atrial septal defect up to a stretched diameter of 26 mm [27].
  • The atrial septal defect was closed, and long-term oral prostacyclin therapy was initiated [28].
  • Preoperative prostaglandin E1 therapy in a patient with atrial septal defect and predominant right-to-left shunting [29].

Regulatory relationships of ASD1


Other interactions of ASD1


Analytical, diagnostic and therapeutic context of ASD1


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  8. Patient with partial trisomy 9q and learning disability but no pyloric stenosis. Hengstschläger, M., Prusa, A.R., Repa, C., Drahonsky, R., Deutinger, J., Pollak, A., Bernaschek, G. Developmental medicine and child neurology. (2004) [Pubmed]
  9. Mutation in myosin heavy chain 6 causes atrial septal defect. Ching, Y.H., Ghosh, T.K., Cross, S.J., Packham, E.A., Honeyman, L., Loughna, S., Robinson, T.E., Dearlove, A.M., Ribas, G., Bonser, A.J., Thomas, N.R., Scotter, A.J., Caves, L.S., Tyrrell, G.P., Newbury-Ecob, R.A., Munnich, A., Bonnet, D., Brook, J.D. Nat. Genet. (2005) [Pubmed]
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  12. Survival analysis and risk factors for mortality in transplantation and staged surgery for hypoplastic left heart syndrome. Jenkins, P.C., Flanagan, M.F., Jenkins, K.J., Sargent, J.D., Canter, C.E., Chinnock, R.E., Vincent, R.N., Tosteson, A.N., O'Connor, G.T. J. Am. Coll. Cardiol. (2000) [Pubmed]
  13. Reversal of pulmonary hypertension and subsequent repair of atrial septal defect after treatment with continuous intravenous epoprostenol. Frost, A.E., Quiñones, M.A., Zoghbi, W.A., Noon, G.P. J. Heart Lung Transplant. (2005) [Pubmed]
  14. Use of prostaglandin E1 in infants with d-transposition of the great arteries and intact ventricular septum. Lang, P., Freed, M.D., Bierman, F.Z., Norwood, W.I., Nadas, A.S. Am. J. Cardiol. (1979) [Pubmed]
  15. Post-infarction peripheral cysts of the lung in pediatric patients: a possible cause of idiopathic spontaneous pneumothorax. Stocker, J.T., McGill, L.C., Orsini, E.N. Pediatr. Pulmonol. (1985) [Pubmed]
  16. Percutaneous closure of atrial septal defect via transjugular approach with the Amplatzer septal occluder after unsuccessful attempt using the CardioSEAL device. Sullebarger, J.T., Sayad, D., Gerber, L., Ettedgui, J., Jimmo-Waumans, S., Alcebo, P.C. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. (2004) [Pubmed]
  17. Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways. Benson, D.W., Silberbach, G.M., Kavanaugh-McHugh, A., Cottrill, C., Zhang, Y., Riggs, S., Smalls, O., Johnson, M.C., Watson, M.S., Seidman, J.G., Seidman, C.E., Plowden, J., Kugler, J.D. J. Clin. Invest. (1999) [Pubmed]
  18. Assessment of left ventricular function in secundum atrial septal defect by computer analysis of the M-mode echocardiogram. St John Sutton, M.G., Tajik, A.J., Mercier, L.A., Seward, J.B., Giuliani, E.R., Ritman, E.L. Circulation (1979) [Pubmed]
  19. Pressure and volume loading of the right ventricle have opposite effects on left ventricular ejection fraction. Louie, E.K., Lin, S.S., Reynertson, S.I., Brundage, B.H., Levitsky, S., Rich, S. Circulation (1995) [Pubmed]
  20. The spectrum of cardiac defects in the Ehlers-Danlos syndrome, types I and III. Leier, C.V., Call, T.D., Fulkerson, P.K., Wooley, C.F. Ann. Intern. Med. (1980) [Pubmed]
  21. Effect of atrial septal defect repair on left ventricular geometry and degree of mitral valve prolapse. Schreiber, T.L., Feigenbaum, H., Weyman, A.E. Circulation (1980) [Pubmed]
  22. Surgical alternatives to the Fontan procedure incorporating a hypoplastic right ventricle. Gentles, T.L., Keane, J.F., Jonas, R.A., Marx, G.E., Mayer, J.E. Circulation (1994) [Pubmed]
  23. Mitral valve prolapse. Devereux, R.B., Perloff, J.K., Reichek, N., Josephson, M.E. Circulation (1976) [Pubmed]
  24. Partial biventricular repair of pulmonary atresia with intact ventricular septum. Use of an adjustable atrial septal defect. Laks, H., Pearl, J.M., Drinkwater, D.C., Jarmakani, J., Isabel-Jones, J., George, B.L., Williams, R.G. Circulation (1992) [Pubmed]
  25. Myocardial catecholamine metabolism in patients with chronic aortic regurgitation. Mäurer, W., Ablasser, A., Tschada, R., Hausen, M., Saggau, W., Kübler, W. Circulation (1982) [Pubmed]
  26. Pulmonary blood flow alters nitric oxide production in patients undergoing device closure of atrial septal defects. Tworetzky, W., Moore, P., Bekker, J.M., Bristow, J., Black, S.M., Fineman, J.R. J. Am. Coll. Cardiol. (2000) [Pubmed]
  27. Transcatheter closure of secundum atrial septal defects with the new self-centering Amplatzer Septal Occluder. Fischer, G., Kramer, H.H., Stieh, J., Harding, P., Jung, O. Eur. Heart J. (1999) [Pubmed]
  28. Reduction in recalcitrant pulmonary hypertension after operation for atrial septal defect. Yamauchi, H., Yamaki, S., Fujii, M., Iwaki, H., Tanaka, S. Ann. Thorac. Surg. (2001) [Pubmed]
  29. Preoperative prostaglandin E1 therapy in a patient with atrial septal defect and predominant right-to-left shunting. Trantina, A.E., Mächler, H., Kulier, A., Bergmann, P., Dacar, D., Müller, H., Oberwalder, P., Zenker, G., Rigler, B. Anesth. Analg. (1998) [Pubmed]
  30. Latent hypoparathyroidism in children with conotruncal cardiac defects. Cuneo, B.F., Langman, C.B., Ilbawi, M.N., Ramakrishnan, V., Cutilletta, A., Driscoll, D.A. Circulation (1996) [Pubmed]
  31. Developmental paradigms in heart disease: insights from tinman. Prall, O.W., Elliott, D.A., Harvey, R.P. Ann. Med. (2002) [Pubmed]
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  33. Erythropoietin, erythropoesis and iron status in children after major surgical stress. Aufricht, C., Ties, M., Salzer-Muhar, U., Wimmer, M., Herkner, K., Haschke, F. Eur. J. Pediatr. (1995) [Pubmed]
  34. A novel GATA4 mutation completely segregated with atrial septal defect in a large Japanese family. Okubo, A., Miyoshi, O., Baba, K., Takagi, M., Tsukamoto, K., Kinoshita, A., Yoshiura, K., Kishino, T., Ohta, T., Niikawa, N., Matsumoto, N. J. Med. Genet. (2004) [Pubmed]
  35. Mutations in the EGF-CFC Gene Cryptic Are an Infrequent Cause of Congenital Heart Disease. Ozcelik, C., Bit-Avragim, N., Panek, A., Gaio, U., Geier, C., Lange, P.E., Dietz, R., Posch, M.G., Perrot, A., Stiller, B. Pediatric cardiology (2006) [Pubmed]
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  38. Mitral cleft in ostium primum atrial septal defect assessed by cross-sectional echocardiography. Beppu, S., Nimura, Y., Sakakibara, H., Nagata, S., Park, Y.D., Baba, K., Naito, Y., Ohta, M., Kamiya, T., Koyanagi, H., Fujita, T. Circulation (1980) [Pubmed]
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  40. Double-umbrella closure of atrial defects. Initial clinical applications. Rome, J.J., Keane, J.F., Perry, S.B., Spevak, P.J., Lock, J.E. Circulation (1990) [Pubmed]
  41. Noninvasive evaluation of the ratio of pulmonary to systemic flow in atrial septal defect by duplex Doppler echocardiography. Kitabatake, A., Inoue, M., Asao, M., Ito, H., Masuyama, T., Tanouchi, J., Morita, T., Hori, M., Yoshima, H., Ohnishi, K. Circulation (1984) [Pubmed]
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