Disease relevance of Hares

• Isonicotinic acid hydrazide (INH) inhibits the growth of Corynebacterium lepus on hexadecane but has no effect on its growth on fructose [1].
• Anaplasma marginale in Lepus nigricollis (Blanford) treated with oxytetracycline [2].

High impact information on Hares

• The female hybrid hare (Lepus timidus x Lepus europaeus) is heterozygous for electrophoretically separable, X-linked isoenzymes of glucose-6-phosphate dehydrogenase [3].
• Seasonal variation in the daily pattern of plasma melatonin in a wild mammal: the mountain hare (Lepus timidus) [4].
• A 587 bp fragment of cytochrome b sequences from 90 individuals of 15 hare (Lepus) species and two outgroups were phylogenetically analysed and compared to an analysis derived from 474 bp sequences of the nuclear transferrin gene [5].
• Autoradiographic distribution of peripheral benzodiazepine receptors in the retina of the albino rabbit, Lepus cunicula [6].
• The distribution of peripheral benzodiazepine receptors (PBRs) in the retina of the albino rabbit, Lepus cunicula, was studied by autoradiography using [3H]-PK11195, a isoquinoline carboxamide, as a tracer [6].

Biological context of Hares

• Preliminary results on plasma progesterone levels during pregnancy and superfetation in the hare, Lepus Europaeus [7].
• To this end, we have collected DNA sequence data from a 702-bp region of the mitochondrial cytochrome b gene and reconstructed the evolutionary history (via parsimony, neighbor joining, and maximum likelihood) of 11 species of Lepus, focusing on North American taxa [8].
• Cytochrome b phylogeny of North American hares and jackrabbits (Lepus, lagomorpha) and the effects of saturation in outgroup taxa [8].

Associations of Hares with chemical compounds

• Plasma progesterone levels during pregnancy and pseudo-pregnancy in the hare (Lepus europaeus syriacus) [9].
• The primary effect of INH appears to be inhibition of mycolic acid synthesis, which limits the growth of C. lepus on hexadecane by reducing the concentration of bioemulsifier [1].
• Steroid biosynthesis by adrenal tissue of snowshoe hares (Lepus americanus) collected in a year of peak population density [10].
• Accumulation of lead, cadmium, and mercury in liver and kidney of the brown hare (Lepus europaeus) in relation to the season, age, and sex in the West Slovakian Lowland [11].
• 2. L-gulonolactone oxidase activity is low and tissue ascorbate high during all seasons in snowshoe hares (Lepus americanus) [12].

Gene context of Hares

• Vaal ribbok (Pelea capreolus), bontebok (Damaliscus dorcas dorcas) and scrub hares (Lepus saxatilis) were slaughtered in the Bontebok National Park at regular intervals and examined for arthropod parasites [13].
• Only one system, carbonic anhydrase (CA-I), proved useful in species identification, this being restricted to the genus Lepus [14].
• Scrub hares, Lepus saxatilis, and Cape hares, Lepus capensis, harboured the largest number of tick species [15].

References