Disease relevance of Centaurea

• Inhibition of tomato bushy stunt virus infection using a quercetagetin flavonoid isolated from Centaurea rupestris L [1].

High impact information on Centaurea

• Enantiomeric-dependent phytotoxic and antimicrobial activity of (+/-)-catechin. A rhizosecreted racemic mixture from spotted knapweed [2].
• Inactivation of the cytotoxic activity of repin, a sesquiterpene lactone from Centaurea repens [3].
• Repin, a principal ingredient purified from Russian knapweed, is a sesquiterpene lactone containing an alpha-methylenebutyrolactone moiety and epoxides and is a highly reactive electrophile that can readily undergo conjugation with various biological nucleophiles, such as proteins, DNA, and glutathione (GSH) [4].
• Purification, cloning and autoproteolytic processing of an aspartic proteinase from Centaurea calcitrapa [5].
• Preliminary study of the potential vasodilator effects on rat aorta of centaurein and centaureidin, two flavonoids from Centaurea corcubionensis [6].

Biological context of Centaurea

• Biomimetic cyclization of cnicin to malacitanolide, a cytotoxic eudesmanolide from Centaurea malacitana [7].

Anatomical context of Centaurea

• Bioassay-guided fractionation of extracts from Centaurea species using the PC12 cell line have led to the identification of one of several putative agents, which may contribute to ENE, namely, the sesquiterpene lactone (SQL) repin (1), previously linked to ENE due to its abundance in C. repens [3].

Associations of Centaurea with chemical compounds

• Aerial parts of Centaurea napifolia furnished the sesquiterpene lactones cnicin, 4'-acetoxycnicin, melitensin, dehydromelitensin, two known esters of dehydromelitensin, lappaol and a lappaol isomer, and a 1,2-diacylated glucose [8].
• Flavonoid glycosides from Centaurea pseudoscabiosa subsp. pseudoscabiosa from Turkey [9].
• Preparative RP-HPLC analysis of a methanol extract of the seeds of Centaurea cyanus afforded four indole alkaloids: moschamine, cis-moschamine, centcyamine and cis-centcyamine, the latter two being new natural products [10].
• Isolation, NMR studies, and biological activities of onopordopicrin from Centaurea sonchifolia [11].
• The noxious weed yellow starthistle (Centaurea solstitialis L.) can be controlled effectively at the seedling stage with foliar application of the auxinic herbicides picloram or clopyralid [12].

Gene context of Centaurea

• The roots of Centaurea bracteata Scop [13].
• In both antioxidant assays strong activity was shown for Leopoldia comosa (bulbs, syn.: Muscari comosum) and Centaurea calcitrapa (young whorls) [14].

References