Disease relevance of Stachys

• Acetoside, a component of Stachys sieboldii MIQ, may be a promising antinephritic agent: effect of acteoside on crescentic-type anti-GBM nephritis in rats [1].

High impact information on Stachys

• Nine species from the genus Stachys L. representing subgenera Stachys and Betonica were surveyed for flavonoid glycosides by means of HPLC coupled to diode-array detection and LC-APCI-MS [2].
• Glycosides of tricetin methyl ethers as chemosystematic markers in Stachys subgenus Betonica [2].
• Those species belonging to subgenus Betonica were characterised by the presence of glycosides of tricetin methyl ethers, including a new derivative, which was isolated from S. scardica Griseb. and identified as tricetin 3',4',5' -trimethyl ether 7-O-beta-glucopyranoside by spectroscopic methods [2].
• From the aerial parts of Stachys officinalis, six new phenylethanoid glycosides, named betonyosides A-F, and six known phenylethanoid glycosides, acetoside, acetoside isomer, campneosides II, forsythoside B and leucosceptoside B, were isolated and their structures were elucidated from spectroscopic and chemical evidence [3].
• Nine phenethyl alcohol glycosides from Stachys sieboldii [4].

Anatomical context of Stachys

• Acteoside, a component of Stachys sieboldii MIQ, may be a promising antinephritic agent (2): Effect of acteoside on leukocyte accumulation in the glomeruli of nephritic rats [5].
• The effects of the methanol extracts of these two endemic Greek Stachys sp. and their main flavonoids were examined on arachidonic acid (AA) metabolism in the cellular system (mouse peritoneal macrophages and human platelets) [6].

Associations of Stachys with chemical compounds

• This type of flavonoid was absent from species belonging to subgenus Stachys and can be considered as a chemosystematic marker for subgenus Betonica [2].
• In the present study, the anti-inflammatory properties of total methanol extract isolated from aerial parts of Stachys inflata were investigated in two well-characterised inflammatory models in rats, carrageenan-induced paw oedema and formalin-induced paw licking [7].
• These results suggested that the extract of Stachys lavandulifolia possessed anxiolytic effect with relatively lower sedative activity than diazepam [8].
• The new flavonoid glycoside stachyspinoside (1), and the three iridoids, 7-O-acetyl-8-epi-loganic acid (2), ajugol (3) and harpagide (4) were isolated from Stachys spinosa [9].
• Two flavonoid glycosides containing acetylated allose, and two iridoid glucosides were obtained from a EtOH extract of Stachys corsica, an endemic plant of Sardinia and Corsica [10].

Gene context of Stachys

• Antioxidant activity of four endemic Stachys taxa [11].

References