The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Rumen

  • Four strains of Butyrivibrio fibrisolvens, transformed with a gene encoding fluoroacetate dehalogenase, maintained a combined population of 10(6) to 10(7) cells ml-1 in the rumens of test sheep [1].
  • Phenol-water extraction of Megasphaera elsdenii, a predominant gram-negative coccus in rumens of cattle fed high-grain diets, yielded material that exhibited typical characteristics of endotoxin [2].

High impact information on Rumen

  • Monensin-resistant bacteria in the rumens of calves on monensin-containing and unmedicated diets [3].
  • The histamine producing bacteria could not be isolated from the rumens of cattle fed hay; however, histamine producing bacteria could be isolated the feces of cattle fed grain and the cecum of a horse [4].
  • In model rumens, B. thetaiotaomicron BTX increased fiber digestion when added to mixed ruminal microbes, independent of chondroitin sulfate addition; but further study is needed to determine effects on other fiber-digesting bacteria [5].
  • The effect of ruminal flora on the disposition of benzimidazole anthelmintic drugs was studied in dual-flow continuous-culture fermenters (artificial rumens) [6].
  • Ruminal pH was lower and both D- and L-lactate concentrations were greater in the rumens of calves fed the 81% TDN diets [7].

Anatomical context of Rumen

  • Palmitate oxidation to 14CO2 by rumen epithelial cells isolated from the rumens of mature sheep was linear during the course of a 2-h incubation (11.1 nmoles.million cells-1.2 h-1) and 3.6 times the rate of palmitate oxidation by cells isolated from neonatal rumen (3.1 nmoles.million cells-1.min-1) [8].

Associations of Rumen with chemical compounds

  • These data indicate that supplemental Cr, as chromium-L-methionine, increased glucose clearance rate after an insulin infusion and increased the insulin response to an intravenous glucose challenge in growing calves with functioning rumens [9].
  • Free [Me-14C]choline is very rapidly cleared from rumen fluid, a little being incorporated into the phosphatidylcholine of protozoa, but the clearance also occurs in animals with defaunated rumens [10].
  • Levels of butyrate, lactate and succinate in the rumens of feedlot cattle were high enough to provide toxic doses of these anions [11].


  1. Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning. Gregg, K., Hamdorf, B., Henderson, K., Kopecny, J., Wong, C. Appl. Environ. Microbiol. (1998) [Pubmed]
  2. Characterization of endotoxin from the rumen bacterium Megasphaera elsdenii. Nagaraja, T.G., Fina, L.R., Lassman, B.A., Bartley, E.E., Anthony, H.D., Sapienza, D.A., Brent, B.E. Am. J. Vet. Res. (1979) [Pubmed]
  3. Monensin-resistant bacteria in the rumens of calves on monensin-containing and unmedicated diets. Dawson, K.A., Boling, J.A. Appl. Environ. Microbiol. (1983) [Pubmed]
  4. Allisonella histaminiformans gen. nov., sp. nov. A novel bacterium that produces histamine, utilizes histidine as its sole energy source, and could play a role in bovine and equine laminitis. Garner, M.R., Flint, J.F., Russell, J.B. Syst. Appl. Microbiol. (2002) [Pubmed]
  5. Persistence and functional impact of a microbial inoculant on native microbial community structure, nutrient digestion and fermentation characteristics in a rumen model. Ziemer, C.J., Sharp, R., Stern, M.D., Cotta, M.A., Whitehead, T.R., Stahl, D.A. Syst. Appl. Microbiol. (2002) [Pubmed]
  6. Effect of ruminal microflora on the biotransformation of netobimin, albendazole, albendazole sulfoxide, and albendazole sulfoxide enantiomers in an artificial rumen. Capece, B.P., Calsamiglia, S., Castells, G., Arboix, M., Cristòfol, C. J. Anim. Sci. (2001) [Pubmed]
  7. Metabolic alterations associated with an attempt to induce laminitis in dairy calves. Momcilovic, D., Herbein, J.H., Whittier, W.D., Polan, C.E. J. Dairy Sci. (2000) [Pubmed]
  8. Palmitate metabolism by isolated sheep rumen epithelial cells. Jesse, B.W., Solomon, R.K., Baldwin, R.L. J. Anim. Sci. (1992) [Pubmed]
  9. Effect of dietary chromium-L-methionine on glucose metabolism of beef steers. Kegley, E.B., Galloway, D.L., Fakler, T.M. J. Anim. Sci. (2000) [Pubmed]
  10. Role of choline in the nutrition of the rumen protozoon Entodinium caudatum. Broad, T.E., Dawson, R.M. J. Gen. Microbiol. (1976) [Pubmed]
  11. Excess rumen product anions in cattle. I. Blood clearance rates and reduced liver function from sublethal doses of volatile fatty acids, lactate and succinate. Bide, R.W. Can. J. Comp. Med. (1983) [Pubmed]
WikiGenes - Universities