High impact information on Polychaeta

• When isolated in the presence of chelating agents, the neurofilaments of Myxicola are composed almost entirely of protein subunits with mol wt of 150,000 and 160,000 [1].
• These results suggest the existence of high-affinity, ATP-independent binding sites for 45Ca in Myxicola axoplasm that compete favorably with 100 microM EGTA [2].
• Quinidine interactions with Myxicola giant axons [3].
• Internal cesium and the sodium inactivation gate in Myxicola giant axons [4].
• In Myxicola axons, substitution of tetramethylammonium (TMA+) for Cs+ alters intramembrane charge movements (gating currents) [5].

Biological context of Polychaeta

• 1. Internal gallamine triethiodide (Flaxedil) modifies Na+ channel kinetics in Myxicola axons but does not alter K+ conductance [6].
• Localization of a vertebrate telomeric sequence in the chromosomes of two marine worms (phylum Annelida: class polychaeta) [7].

Anatomical context of Polychaeta

• The effects of the compounds 2-, 3- and 4-aminopyridine and sparteine on membrane conductance changes were examined using both voltage-clamped Myxicola axons and the lobster neuromuscular junction [8].

Associations of Polychaeta with chemical compounds

• Inhibition of potassium conductance with external tetraethylammonium ion in Myxicola giant axons [9].
• Internal cesium alters sodium inactivation in Myxicola [10].
• Amino acid transport in Myxicola giant axon: stability of the amino acid pool, taurine efflux, and trans effect of sodium [11].
• Gallamine triethiodide-induced modifications of sodium conductance in Myxicola giant axons [6].
• Substitution of heavy water (D2O) for H2O slows the Na+ and K+ currents in Myxicola giant axons by 40-50% at 5 degrees C. In contrast, the delays in Na+ K+ activation which can be produced by hyperpolarizing pre-pulses are not affected by solvent substitution [12].

Gene context of Polychaeta

• 1. Axoplasm from Myxicola contains two major polypeptides associated with neurofilaments, together with actin, tubulin and many minor polypeptide components [13].
• In Myxicola axons the effect of temperature alone on asymmetry current kinetics can be well described via a simple temporal expansion equivalent to a Q10 of 2.2, which is somewhat less than the Q10 of GNa activation [14].
• Antioxidant mechanisms of the Nereidid Laeonereis acuta (Anelida: Polychaeta) to cope with environmental hydrogen peroxide [15].
• The function of the cellular haemoglobins in Capitella capitata (Fabricius) and Notomastus latericeus sars (Capitellidae: Polychaeta) [16].
• Unusual isozyme patterns of glucose-6-phosphate isomerase in Polydora brevipalpa (Polychaeta: Spionidae) [17].

Analytical, diagnostic and therapeutic context of Polychaeta

• The molecular shape and size of the extracellular chlorocruorin of Myxicola infundibulum was determined using scanning transmission electron microscopy and its dissociation in the presence of sodium dodecyl sulfate (SDS) was investigated using polyacrylamide gel electrophoresis [18].

References