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MeSH Review

Leukemia, Radiation-Induced

 
 
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Disease relevance of Leukemia, Radiation-Induced

 

High impact information on Leukemia, Radiation-Induced

 

Biological context of Leukemia, Radiation-Induced

 

Gene context of Leukemia, Radiation-Induced

  • Previous work has demonstrated linkage between Ly-6, H-30, and a locus, Ril-1, that affects susceptibility to radiation-induced leukemia [10].
  • The dose-response relationship for radiation-induced leukemia was examined in a pooled analysis of three exposed populations: Japanese atomic bomb survivors, women treated for cervical cancer, and patients irradiated for ankylosing spondylitis [11].
  • Our laboratory's approach to try to shed light on the question of a viral etiology for radiation-induced leukemia has focused on defining, localizing and understanding the mode of action of genes involved in susceptibility to FXI-induced disease [12].

References

  1. Cell surface antigens of murine leukemias induced by radiation leukemia virus. Recognition of individually distinct cell surface antigens by cytotoxic T cells on leukemias expressing crossreactive transplantation antigens. Morishita, H., Shiku, H., Horibe, K., Obata, Y., Stockert, E., Oettgen, H.F., Old, L.J., Yamada, K. J. Exp. Med. (1986) [Pubmed]
  2. A role for elevated H-2 antigen expression in resistance to neoplasia caused by radiation-induced leukemia virus. Enhancement of effective tumor surveillance by killer lymphocytes. Meruelo, D. J. Exp. Med. (1979) [Pubmed]
  3. Atomic bomb and leukemia. Ichimaru, M., Tomonaga, M., Amenomori, T., Matsuo, T. J. Radiat. Res. (1991) [Pubmed]
  4. Increased synthesis and expression of H-2 antigens on thymocytes as a result of radiation leukemia virus infection: a possible mechanism for H-2 linked control of virus-induced neoplasia. Meruelo, D., Nimelstein, S.H., Jones, P.P., Lieberman, M., McDevitt, H.O. J. Exp. Med. (1978) [Pubmed]
  5. Radiation leukemia in C57BL/6 mice. I. Lack of serological evidence for the role of endogenous ecotropic viruses in pathogenesis. Ihle, J.N., McEwan, R., Bengali, K. J. Exp. Med. (1976) [Pubmed]
  6. Allelic loss on chromosome 4 (Lyr2/TLSR5) is associated with myeloid, B-lympho-myeloid, and lymphoid (B and T) mouse radiation-induced leukemias. Cleary, H., Boulton, E., Plumb, M. Blood (2001) [Pubmed]
  7. Effect of human recombinant granulocyte colony-stimulating factor on induction of myeloid leukemias by X-irradiation in mice. Kawase, Y., Akashi, M., Ohtsu, H., Aoki, Y., Akanuma, A., Suzuki, G. Blood (1993) [Pubmed]
  8. Cytogenetic analysis of radiation-induced leukemia in Trp53-deficient C3H/He mice. Ban, N., Yoshida, K., Aizawa, S., Wada, S., Kai, M. Radiat. Res. (2002) [Pubmed]
  9. Cytogenetic and molecular changes in leukemia found among atomic bomb survivors. Kamada, N. J. Radiat. Res. (1991) [Pubmed]
  10. Assignment of the Ly-6--Ril-1--Sis--H-30--Pol-5/Xmmv-72--Ins-3--Krt-1--Int-1 --Gdc-1 region to mouse chromosome 15. Meruelo, D., Rossomando, A., Scandalis, S., D'Eustachio, P., Fournier, R.E., Roop, D.R., Saxe, D., Blatt, C., Nesbitt, M.N. Immunogenetics (1987) [Pubmed]
  11. Risks of leukemia in Japanese atomic bomb survivors, in women treated for cervical cancer, and in patients treated for ankylosing spondylitis. Little, M.P., Weiss, H.A., Boice, J.D., Darby, S.C., Day, N.E., Muirhead, C.R. Radiat. Res. (1999) [Pubmed]
  12. A molecular and genetic approach to understanding the mechanisms by which fractionated X-irradiation induces leukemia in mice. Meruelo, D., Rossomando, A. Leuk. Res. (1986) [Pubmed]
 
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