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Chemical Compound Review

AC1L1AT8     [5-(6-aminopurin-9-yl)-4- hydroxy-2...

Synonyms:
 
 
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Disease relevance of tigloyl-CoA

  • Methylcrotonyl-CoA and geranyl-CoA carboxylases are involved in leucine/isovalerate utilization (Liu) and acyclic terpene utilization (Atu), and are encoded by liuB/liuD and atuC/atuF, in Pseudomonas aeruginosa [1].
 

High impact information on tigloyl-CoA

 

Anatomical context of tigloyl-CoA

 

Analytical, diagnostic and therapeutic context of tigloyl-CoA

  • We present a patient with methylcrotonyl-CoA carboxylase (MCC) deficiency (McKusick 210200) who suffered from severe muscle pain and physical disability, and propose that this disorder be considered in the differential diagnosis of adult patients presenting with muscle pain and weakness [9].

References

  1. Methylcrotonyl-CoA and geranyl-CoA carboxylases are involved in leucine/isovalerate utilization (Liu) and acyclic terpene utilization (Atu), and are encoded by liuB/liuD and atuC/atuF, in Pseudomonas aeruginosa. Höschle, B., Gnau, V., Jendrossek, D. Microbiology (Reading, Engl.) (2005) [Pubmed]
  2. A novel O-tigloyltransferase for alkaloid biosynthesis in plants. Purification, characterization, and distribution in Lupinus plants. Suzuki, H., Murakoshi, I., Saito, K. J. Biol. Chem. (1994) [Pubmed]
  3. Marginal biotin deficiency during normal pregnancy. Mock, D.M., Quirk, J.G., Mock, N.I. Am. J. Clin. Nutr. (2002) [Pubmed]
  4. Multiple biotin-containing proteins in 3T3-L1 cells. Chandler, C.S., Ballard, F.J. Biochem. J. (1986) [Pubmed]
  5. Mitochondrial acetoacetyl-CoA thiolase (T2) deficiency: T2-deficient patients with "mild" mutation(s) were previously misinterpreted as normal by the coupled assay with tiglyl-CoA. Zhang, G.X., Fukao, T., Rolland, M.O., Zabot, M.T., Renom, G., Touma, E., Kondo, M., Matsuo, N., Kondo, N. Pediatr. Res. (2004) [Pubmed]
  6. Transblot identification of biotin-containing proteins in rat liver. Haneji, T., Koide, S.S. Anal. Biochem. (1989) [Pubmed]
  7. NADH-dependent tiglyl-CoA reduction in disrupted mitochondria of Ascaris suum. Komuniecki, R., Rioux, A., Thissen, J. Mol. Biochem. Parasitol. (1984) [Pubmed]
  8. Comparison of cytosolic and mitochondrial enzyme alterations in the livers of propionic or methylmalonic acidemia: a reduction of cytochrome oxidase activity. Hayasaka, K., Metoki, K., Satoh, T., Narisawa, K., Tada, K., Kawakami, T., Matsuo, N., Aoki, T. Tohoku J. Exp. Med. (1982) [Pubmed]
  9. Methylcrotonyl-CoA carboxylase (MCC) deficiency associated with severe muscle pain and physical disability in an adult. Boneh, A., Baumgartner, M., Hayman, M., Peters, H. J. Inherit. Metab. Dis. (2005) [Pubmed]
 
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