Disease relevance of Citroglucophosphate

• Fourth, hemolysis was much greater in units stored in CPDA-1 for 35 days than in units stored in CPD for 21 days [1].

High impact information on Citroglucophosphate

• The storage of hard-packed red blood cells in citrate-phosphate-dextrose (CPD) and CPD-adenine (CPDA-1) [2].
• It was therefore concluded that newborn red cells obtained from placentas and stored for several weeks in CPD or CPDA-1 media or other media that improve the metabolic profile of these cells may be acceptable for transfusion [3].
• Human lymphocytes stored at 4 C either as leukocyte concentrates (LCs) in citrate-phosphate-dextrose (CPD) or as whole blood anticoagulated with CPD show a rapid and marked decrease in the relative and absolute numbers of thymus derived (T) lymphocytes [4].
• Electron microscopy of citrate-phosphate-dextrose (CPD) buffered bank blood performed over 21 days shows that the normal architecture of erythrocytes, platelets and leucocytes disappears and that deformed organelles, leucocyte "ghosts", cell fragments and microaggregates accumulate [5].
• The transfusion of CPD blood, therefore, is more favorable in terms of oxygen supply, particularly in patients who have had cardiac surgery [6].

Associations of Citroglucophosphate with other chemical compounds

• The ODC was stable whether heparin, ethylene diamine tetra-acetic acid (EDTA) or citrate phosphate dextrose (CPD) were used as anticoagulants, but the latter was associated with higher p50 values than those observed in fresh samples [7].
• Lactate and ammonia were highest in CPD and CPDA-1 samples, indicating more active red blood cell (RBC) metabolism [8].
• Direct antiglobulin tests were performed on untreated, CaCl2 treated, and Re/coagulan treated EDTA, acid-citrate-dextrose (ACD), and citrate-phosphate-dextrose (CPD) samples of whole blood [9].

Gene context of Citroglucophosphate

• Two possible explanations for this finding were considered: first the presence of citrate-phosphate-dextrose (CPD) in plasma but not in serum, and second the presence of platelet-derived growth factor (PDGF) in serum but not in plasma [10].

References