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Chemical Compound Review

AG-J-53647     (6R,7S)-7-[[(5R)-5-amino-5- carboxy...

Synonyms: CHEBI:18065, SureCN11534966, KST-1A2049, KST-1A2050, AC1L4NVC, ...
 
 
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Disease relevance of C03112

 

High impact information on C03112

 

Biological context of C03112

 

Associations of C03112 with other chemical compounds

 

Gene context of C03112

 

Analytical, diagnostic and therapeutic context of C03112

References

  1. Cloning and sequencing of the beta-lactam hydroxylase gene (cefF) from Streptomyces clavuligerus: gene duplication may have led to separate hydroxylase and expandase activities in the actinomycetes. Kovacevic, S., Miller, J.R. J. Bacteriol. (1991) [Pubmed]
  2. Recombinant Acremonium chrysogenum strains for the industrial production of cephalosporin. Díez, B., Mellado, E., Fouces, R., Rodríguez, M., Barredo, J.L. Microbiologia (1996) [Pubmed]
  3. Controlling the substrate selectivity of deacetoxycephalosporin/deacetylcephalosporin C synthase. Lloyd, M.D., Lipscomb, S.J., Hewitson, K.S., Hensgens, C.M., Baldwin, J.E., Schofield, C.J. J. Biol. Chem. (2004) [Pubmed]
  4. Deacetylcephalosporin C Production in Penicillium chrysogenum by Expression of the Isopenicillin N Epimerization, Ring Expansion, and Acetylation Genes. Ullán, R.V., Campoy, S., Casqueiro, J., Fernández, F.J., Martín, J.F. Chem. Biol. (2007) [Pubmed]
  5. Molecular characterization of the Acremonium chrysogenum cefG gene product: the native deacetylcephalosporin C acetyltransferase is not processed into subunits. Velasco, J., Gutierrez, S., Campoy, S., Martin, J.F. Biochem. J. (1999) [Pubmed]
  6. Organization and expression in Pseudomonas putida of the gene cluster involved in cephalosporin biosynthesis from Lysobacter lactamgenus YK90. Kimura, H., Miyashita, H., Sumino, Y. Appl. Microbiol. Biotechnol. (1996) [Pubmed]
  7. Cloning and characterization of the gene cahB encoding a cephalosporin C acetylhydrolase from Acremonium chrysogenum. Velasco, J., Gutiérrez, S., Casqueiro, J., Fierro, F., Campoy, S., Martín, J.F. Appl. Microbiol. Biotechnol. (2001) [Pubmed]
  8. Cloning and disruption of the cefG gene encoding acetyl coenzyme A: deacetylcephalosporin C o-acetyltransferase from Acremonium chrysogenum. Matsuda, A., Sugiura, H., Matsuyama, K., Matsumoto, H., Ichikawa, S., Komatsu, K. Biochem. Biophys. Res. Commun. (1992) [Pubmed]
  9. Exogenous methionine increases levels of mRNAs transcribed from pcbAB, pcbC, and cefEF genes, encoding enzymes of the cephalosporin biosynthetic pathway, in Acremonium chrysogenum. Velasco, J., Gutierrez, S., Fernandez, F.J., Marcos, A.T., Arenos, C., Martin, J.F. J. Bacteriol. (1994) [Pubmed]
  10. The cefG gene of Cephalosporium acremonium is linked to the cefEF gene and encodes a deacetylcephalosporin C acetyltransferase closely related to homoserine O-acetyltransferase. Gutiérrez, S., Velasco, J., Fernandez, F.J., Martín, J.F. J. Bacteriol. (1992) [Pubmed]
  11. Expression of the cefG gene is limiting for cephalosporin biosynthesis in Acremonium chrysogenum. Gutiérrez, S., Velasco, J., Marcos, A.T., Fernández, F.J., Fierro, F., Barredo, J.L., Díez, B., Martín, J.F. Appl. Microbiol. Biotechnol. (1997) [Pubmed]
  12. Molecular cloning of acetyl coenzyme A: deacetylcephalosporin C o-acetyltransferase cDNA from Acremonium chrysogenum: sequence and expression of catalytic activity in yeast. Matsuda, A., Sugiura, H., Matsuyama, K., Matsumoto, H., Ichikawa, S., Komatsu, K. Biochem. Biophys. Res. Commun. (1992) [Pubmed]
  13. Occurrence of a new cephalosporoate in a culture broth of a Cephalosporium acremonium mutant. Fujisawa, Y., Kanzaki, T. J. Antibiot. (1975) [Pubmed]
 
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