Chemical Compound Review:
CGS-8515 methyl 2-[(3,4-dioxonaphthalen-1...
Synonyms:
ACMC-1C4N1, AG-J-90901, SureCN3273068, AC1L4TWI, AC1Q5ZBK, ...
- Inhibition of leukotriene release in anaphylactic guinea-pig hearts by a 5-lipoxygenase inhibitor, CGS 8515. Yaacob, H.B., Piper, P.J. Br. J. Pharmacol. (1988)
- Modulation of arachidonic acid metabolites and vulnerability to ventricular fibrillation during myocardial ischemia in the cat. Cooper, D.R., Kelliher, G.J., Kowey, P.R. Am. Heart J. (1988)
- Effects of cyclooxygenase and lipoxygenase inhibitors on digoxin-induced arrhythmias and haemodynamics in guinea-pigs. Kanzik, I., Cakici, I., Ersoy, S., Ark, M., Abacioglu, N., Zengil, H. Pharmacol. Res. (1992)
- Pharmacokinetic screening of o-naphthoquinone 5-lipoxygenase inhibitors. Rakhit, A., Kuwahara, S.K., Jones, D.R., Soliman, V.F., Kotake, A.N., Oglesby, T.D., Wasley, J.W., Tripp, S.L., Douglas, F.L. Pharm. Res. (1990)
- Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor. Olson, N.C., Kruse-Elliott, K.T., Johnson, L.W. Prostaglandins Leukot. Essent. Fatty Acids (1993)
- Bradykinin-induced responses in a coaxial bioassay system composed of rat anococcygeus muscle and guinea pig trachea. Tunçtan, B., Cakici, I., Abacioğlu, N., Kanzik, I. Gen. Pharmacol. (1998)
- Effects of platelet-activating factor antagonists WEB 2086 and BN 50730 on digoxin-induced arrhythmias. Cakici, I., Mataraci, N., Ersoy, S., Tunçtan, B., Abacioğlu, N., Kanzik, I. Pharmacol. Toxicol. (1995)
- Characterization of CGS 8515 as a selective 5-lipoxygenase (5-LO) inhibitor. Ku, E.C., Raychaudhuri, A., Ghai, G., Kimble, E.F., Lee, W.H., Colombo, C., Dotson, R., White, D., Oglesby, T.D., Wasley, J.W. Adv. Prostaglandin Thromboxane Leukot. Res. (1989)
- Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models. Ku, E.C., Raychaudhuri, A., Ghai, G., Kimble, E.F., Lee, W.H., Colombo, C., Dotson, R., Oglesby, T.D., Wasley, J.W. Biochim. Biophys. Acta (1988)
- CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. Kruse-Elliott, K.T., Olson, N.C. Am. J. Physiol. (1993)
- Determination of the 5-lipoxygenase inhibitor (CGS 8515) in plasma by high-performance liquid chromatography using reductive electrochemical detection. Kuwahara, S.K., Brubaker, W.F., Williams, E., Tripp, S., Douglas, F.L., Kotake, A.N. J. Chromatogr. (1990)