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Chemical Compound Review

Hepamerz     [(4S)-4-amino-4-carboxy- butyl]azanium;...

Synonyms: Orparan, Ormeta, Hepa-Merz, AC1L2CEO, LS-22126, ...
 
 
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Disease relevance of Ornithine L-form aspartate

 

High impact information on Ornithine L-form aspartate

 

Chemical compound and disease context of Ornithine L-form aspartate

 

Biological context of Ornithine L-form aspartate

 

Associations of Ornithine L-form aspartate with other chemical compounds

 

Analytical, diagnostic and therapeutic context of Ornithine L-form aspartate

References

  1. Therapeutic efficacy of L-ornithine-L-aspartate infusions in patients with cirrhosis and hepatic encephalopathy: results of a placebo-controlled, double-blind study. Kircheis, G., Nilius, R., Held, C., Berndt, H., Buchner, M., Görtelmeyer, R., Hendricks, R., Krüger, B., Kuklinski, B., Meister, H., Otto, H.J., Rink, C., Rösch, W., Stauch, S. Hepatology (1997) [Pubmed]
  2. L-ornithine-L-aspartate lowers plasma and cerebrospinal fluid ammonia and prevents brain edema in rats with acute liver failure. Rose, C., Michalak, A., Rao, K.V., Quack, G., Kircheis, G., Butterworth, R.F. Hepatology (1999) [Pubmed]
  3. Effect of L-ornithine-L-aspartate on patients with and without TIPS undergoing glutamine challenge: a double blind, placebo controlled trial. Rees, C.J., Oppong, K., Al Mardini, H., Hudson, M., Record, C.O. Gut (2000) [Pubmed]
  4. Alterations in expression of genes coding for key astrocytic proteins in acute liver failure. Desjardins, P., Bélanger, M., Butterworth, R.F. J. Neurosci. Res. (2001) [Pubmed]
  5. Oral L-ornithine-L-aspartate therapy of chronic hepatic encephalopathy: results of a placebo-controlled double-blind study. Stauch, S., Kircheis, G., Adler, G., Beckh, K., Ditschuneit, H., Görtelmeyer, R., Hendricks, R., Heuser, A., Karoff, C., Malfertheiner, P., Mayer, D., Rösch, W., Steffens, J. J. Hepatol. (1998) [Pubmed]
  6. Pharmacokinetics and bioavailability study of L-ornithine-L-aspartate in healthy volunteers--a comparative study of two oral formulations. Kowalski, P., Bieniecki, M. Journal of pharmaceutical and biomedical analysis. (2006) [Pubmed]
  7. L-ornithine-L-aspartate in experimental portal-systemic encephalopathy: therapeutic efficacy and mechanism of action. Rose, C., Michalak, A., Pannunzio, P., Therrien, G., Quack, G., Kircheis, G., Butterworth, R.F. Metabolic brain disease. (1998) [Pubmed]
  8. Clinical efficacy of L-ornithine-L-aspartate in the management of hepatic encephalopathy. Kircheis, G., Wettstein, M., Dahl, S., Häussinger, D. Metabolic brain disease. (2002) [Pubmed]
  9. Intravenous loading with arginine-hydrochloride and ornithine-aspartate in siblings of two families, presenting a familial neurological syndrome associated with cystinuria. Strauven, T., Mardens, Y., Clara, R., Terheggen, H. Biomedicine / [publiée pour l'A.A.I.C.I.G.]. (1976) [Pubmed]
  10. Validated method for L-ornithine-L-aspartate analysis in human plasma by capillary electrophoresis. Kowalski, P., Bieniecki, M., Oledzka, I., Lamparczyk, H. Biomed. Chromatogr. (2006) [Pubmed]
  11. X-ray studies on crystalline complexes involving amino acids and peptides. IX. Crystal structure of L-ornithine L-aspartate hemihydrate. Salunke, D.M., Vijayan, M. Int. J. Pept. Protein Res. (1983) [Pubmed]
  12. Effect of ascorbic acid, alpha-tocopherol, lecithin and L-ornithine-L-aspartate on ethanol induced hypoproteinemia and hyperlipidemia in rats. Maneesh, M., Jayalekshmi, H. Indian J. Physiol. Pharmacol. (2005) [Pubmed]
 
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