Disease relevance of sodium fluoride

• The combination of sodium flouride and calcium carbonate produces new bone formation; it seems a useful adjunct in treatment for myelomatous bone disease [1].
• Clinical evaluation of sodium flouride chewable tablets in dental caries [2].

High impact information on sodium fluoride

• To test for the possible origin of these labeled cells from monocytes, we examined them for the presence of sodium fluoride- (NaF) sensitive non-specific esterase (NSE), an enzyme characteristic of monocytes [3].
• The phosphorylation of the ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit is strongly enhanced when sodium fluorure is used as a protein phosphatase inhibitor [4].
• To study the mode of action of cimetidine the modification of stimulatory effects of histamine, sodium flouride and 5'-guanylylimidodiphosphate by cimetidine on the adenylate cyclase activity of guinea pig gastric mucosa was studied [5].
• Madin-Darby Bovine Kidney cells were treated with sodium flouride, iodoacetate, and 2-deosyglucose, reagents that block glycolysis, and thus reduce phagocytosis [6].
• In all studies, both the plaque indices used found that the active products Colgate Total, Colgate Total plus Whitening and PerioGard produced significantly lower mean plaque scores compared to Colgate Regular Dental Cream and Fluorigard (p < 0.05) [7].

Anatomical context of sodium fluoride

• The three toothpastes used (Merfluan powder, Merfluan paste and Fluorigard) were applied on dentin surfaces using a small sponge to completely cover the dentin surface [8].

References