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MeSH Review

Dental Caries

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Disease relevance of Dental Caries


Psychiatry related information on Dental Caries


High impact information on Dental Caries


Chemical compound and disease context of Dental Caries


Biological context of Dental Caries


Anatomical context of Dental Caries


Gene context of Dental Caries

  • RESULTS: Mice homozygous for the rd12 mutation showed small punctate white spots on fundus examination at 5 months of age [27].
  • The ORF wsv112 of shrimp white spot syndrome virus (WSSV) was predicted to encode a protein with five conserved motifs at its N-terminus characteristics of dUTPases [28].
  • Streptococcus mutans produces a number of extracellular sucrose-metabolizing enzymes that contribute to the ability of the organism to cause dental caries, including three glucosyltransferases, the products of the gtfB, gtfC and gtfD genes, and a fructosyltransferase, encoded by the ftf gene [29].
  • Dental practitioners and parents should consider ADHD to be a condition that may affect children's dental caries experience [30].
  • PCNA-positive pulp cells were detected only in advanced dental caries (grades 3 and 4), and the difference in immuno-positive rate was significant between the two grades (p <0.001) [31].

Analytical, diagnostic and therapeutic context of Dental Caries


  1. Peptide mapping of a novel discontinuous epitope of the major surface adhesin from Streptococcus mutans. van Dolleweerd, C.J., Kelly, C.G., Chargelegue, D., Ma, J.K. J. Biol. Chem. (2004) [Pubmed]
  2. Structural integrity of host defense factors in dental plaque. Hsu, S.D., Cole, M.F. Infect. Immun. (1985) [Pubmed]
  3. Tonsillar application of formalin-killed cells of Streptococcus sobrinus reduces experimental dental caries in rabbits. Fukuizumi, T., Inoue, H., Tsujisawa, T., Uchiyama, C. Infect. Immun. (1999) [Pubmed]
  4. Roles of fructosyltransferase and levanase-sucrase of Actinomyces naeslundii in fructan and sucrose metabolism. Bergeron, L.J., Burne, R.A. Infect. Immun. (2001) [Pubmed]
  5. Provider compliance with recommended dietary fluoride supplement protocol. Levy, S.M., Muchow, G. American journal of public health. (1992) [Pubmed]
  6. Physicians' roles in preventing dental caries in preschool children: a summary of the evidence for the U.S. Preventive Services Task Force. Bader, J.D., Rozier, R.G., Lohr, K.N., Frame, P.S. American journal of preventive medicine. (2004) [Pubmed]
  7. Japanese family with an autosomal dominant chromosome instability syndrome: a new neurodegenerative disease? Ishikawa, S., Ishikawa, M., Tokuda, T., Yoshida, K., Wakui, K., Matsuura, S., Ohara, S., Sekijima, Y., Hidaka, E., Fukushima, Y., Shigeta, H., Komatsu, K., Ikeda, S. Am. J. Med. Genet. (2000) [Pubmed]
  8. Association of pediatric dental caries with passive smoking. Aligne, C.A., Moss, M.E., Auinger, P., Weitzman, M. JAMA (2003) [Pubmed]
  9. Editorial: Value of fluoride supplements in prevention of dental caries. Margolis, F.J. JAMA (1975) [Pubmed]
  10. Sugars and dental decay. Sheiham, A. Lancet (1983) [Pubmed]
  11. Mitosis-specific monoclonal antibody MPM-2 inhibits Xenopus oocyte maturation and depletes maturation-promoting activity. Kuang, J., Zhao, J., Wright, D.A., Saunders, G.F., Rao, P.N. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  12. Xylitol and dental caries. Mäkinen, K.K., Scheinin, A. Annu. Rev. Nutr. (1982) [Pubmed]
  13. Nutritional significance of fructose and sugar alcohols. Wang, Y.M., van Eys, J. Annu. Rev. Nutr. (1981) [Pubmed]
  14. Effects of local immunization with glucosyltransferase fractions from Streptococcus mutans on dental caries in rats and hamsters. Taubman, M.A., Smith, D.J. J. Immunol. (1977) [Pubmed]
  15. The lipopolysaccharide and beta-1,3-glucan binding protein gene is upregulated in white spot virus-infected shrimp (Penaeus stylirostris). Roux, M.M., Pain, A., Klimpel, K.R., Dhar, A.K. J. Virol. (2002) [Pubmed]
  16. Streptococcus mutans H2O2-forming NADH oxidase is an alkyl hydroperoxide reductase protein. Poole, L.B., Higuchi, M., Shimada, M., Calzi, M.L., Kamio, Y. Free Radic. Biol. Med. (2000) [Pubmed]
  17. Oral passive immunization against dental caries in rats by use of hen egg yolk antibodies specific for cell-associated glucosyltransferase of Streptococcus mutans. Hamada, S., Horikoshi, T., Minami, T., Kawabata, S., Hiraoka, J., Fujiwara, T., Ooshima, T. Infect. Immun. (1991) [Pubmed]
  18. Non-cariogenicity of the disaccharide palatinose in experimental dental caries of rats. Ooshima, T., Izumitani, A., Sobue, S., Okahashi, N., Hamada, S. Infect. Immun. (1983) [Pubmed]
  19. Neil Goldsworthy and his legacy: Sydney's Institute of Dental Research. Knox, K.W. J. Dent. Res. (1999) [Pubmed]
  20. Identification of the thymidylate synthase within the genome of white spot syndrome virus. Li, Q., Pan, D., Zhang, J.H., Yang, F. J. Gen. Virol. (2004) [Pubmed]
  21. Reactionary dentinogenesis. Smith, A.J., Cassidy, N., Perry, H., Bègue-Kirn, C., Ruch, J.V., Lesot, H. Int. J. Dev. Biol. (1995) [Pubmed]
  22. The effect of a bi-annual professional application of APF foam on dental caries increment in primary teeth: 24-month clinical trial. Jiang, H., Bian, Z., Tai, B.J., Du, M.Q., Peng, B. J. Dent. Res. (2005) [Pubmed]
  23. Failure to demonstrate an association between enamel fluoride concentration and dental caries in the deciduous dentition. Englander, H.R., Mellberg, J.R. J. Dent. Res. (1976) [Pubmed]
  24. Expression of type I collagen pro-alpha 2 chain mRNA in adult human permanent teeth as revealed by in situ hybridization. Lukinmaa, P.L., Vaahtokari, A., Vainio, S., Thesleff, I. J. Dent. Res. (1992) [Pubmed]
  25. NF-kappaB activation in human dental pulp stem cells by TNF and LPS. Chang, J., Zhang, C., Tani-Ishii, N., Shi, S., Wang, C.Y. J. Dent. Res. (2005) [Pubmed]
  26. Is there a difference in dental caries between myopic and nonmyopic children? Edwards, M.H., Chan, J.C. Optometry and vision science : official publication of the American Academy of Optometry. (1995) [Pubmed]
  27. Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA). Pang, J.J., Chang, B., Hawes, N.L., Hurd, R.E., Davisson, M.T., Li, J., Noorwez, S.M., Malhotra, R., McDowell, J.H., Kaushal, S., Hauswirth, W.W., Nusinowitz, S., Thompson, D.A., Heckenlively, J.R. Mol. Vis. (2005) [Pubmed]
  28. Identification and function of a shrimp white spot syndrome virus (WSSV) gene that encodes a dUTPase. Liu, X., Yang, F. Virus Res. (2005) [Pubmed]
  29. Regulation of the gtfBC and ftf genes of Streptococcus mutans in biofilms in response to pH and carbohydrate. Li, Y., Burne, R.A. Microbiology (Reading, Engl.) (2001) [Pubmed]
  30. Is attention-deficit hyperactivity disorder a risk factor for dental caries? A case-control study. Broadbent, J.M., Ayers, K.M., Thomson, W.M. Caries Res. (2004) [Pubmed]
  31. Biological behavior of human dental pulp cells in response to carious stimuli analyzed by PCNA immunostaining and AgNOR staining. Kobayashi, I., Izumi, T., Okamura, K., Matsuo, K., Ishibashi, Y., Sakai, H. Caries Res. (1996) [Pubmed]
  32. Periodic health examination, 1995 update: 2. Prevention of dental caries. The Canadian Task Force on the Periodic Health Examination. Lewis, D.W., Ismail, A.I. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. (1995) [Pubmed]
  33. The effects of benzoate and fluoride on dental caries in intact and desalivated rats. Davis, B.A., Raubertas, R.F., Pearson, S.K., Bowen, W.H. Caries Res. (2001) [Pubmed]
  34. Clinical outcomes of risk-based caries prevention in preschool-aged children. Pienihäkkinen, K., Jokela, J. Community dentistry and oral epidemiology. (2002) [Pubmed]
  35. Use of polymerase chain reaction techniques and sodium dodecyl sulfate-polyacrylamide gel electrophoresis for differentiation of oral Lactobacillus species. Teanpaisan, R., Dahlén, G. Oral Microbiol. Immunol. (2006) [Pubmed]
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