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Chemical Compound Review

Hinosan     (ethoxy-phenylsulfanyl...

Synonyms: Edifenphos, Ediphenphos, Bay-hinosan, SureCN20330, PS2066_SUPELCO, ...
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Disease relevance of Hinosan


High impact information on Hinosan

  • The cytogenetic and cytotoxic effects of the pesticides methyl parathion, Bayleton and Hinosan were evaluated in mammalian test systems [3].
  • Lipid peroxidation in hepatocytes was stimulated by five pesticides at 10(-3) M, with edifenphos being the most potent peroxidant [4].
  • Although treatment with 2 or 4 mg/kg/d edifenphos did not change the number of healthy and atretic follicles, a dosage of 4 mg/kg/d significantly decreased the number and duration of estrous cycles [1].
  • A significant decrease in stage I, II, III and total number of healthy follicles, and a significant increase in stage I, III, IV and total number of atretic follicles were observed in 0.3 mg edifenphos treated rats [5].
  • Membrane-bound chitin synthase preparations from P. oryzae grown in medium containing 3 or 6 microM-edifenphos had, at the same fungicide concentration, a lower rate of in vivo chitin synthesis than preparations isolated from biomass grown in the absence of edifenphos [6].

Associations of Hinosan with other chemical compounds


Analytical, diagnostic and therapeutic context of Hinosan


  1. Effect of edifenphos on compensatory ovarian hypertrophy, follicular kinetics and estrous cycle in hemicastrated rats. Nanda, N., Kaliwal, B.B. Journal of basic and clinical physiology and pharmacology. (2003) [Pubmed]
  2. Serum transaminases & alkaline phosphatase activities during subacute toxicity of hinosan in Bubalus bubalis. Malik, J.K., Garg, B.D., Verma, S.P., Ahmad, A. Indian J. Exp. Biol. (1978) [Pubmed]
  3. Mutagenic potential of acute exposure to organophosphorus and organochlorine compounds. Vijayaraghavan, M., Nagarajan, B. Mutat. Res. (1994) [Pubmed]
  4. Effects of pesticides on isolated rat hepatocytes, mitochondria, and microsomes. Yamano, T., Morita, S. Arch. Environ. Contam. Toxicol. (1993) [Pubmed]
  5. Effect of edifenphos on follicular dynamics in albino rats. Math, J.R., Jadaramkunti, U.C., Kaliwal, B.B. Indian J. Exp. Biol. (1998) [Pubmed]
  6. Inhibition of phosphatidylcholine and chitin biosynthesis in Pyricularia oryzae, Botrytis fabae and Fusarium graminearum by edifenphos. Binks, P.R., Robson, G.D., Goosey, M.W., Trinci, A.P. J. Gen. Microbiol. (1993) [Pubmed]
  7. Biochemical changes in liver and plasma of rats after oral administration of edifenphos. Poul, J.M. Toxicol. Lett. (1983) [Pubmed]
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