Chemical Compound Review:
Dexoxadrolum (2S)-2-[(4R)-2,2-diphenyl- 1,3-dioxolan-4...
Synonyms:
AC1MHWRP, SureCN24683, CHEMBL1165411, PDSP1_000674, PDSP2_000664, ...
- Comparison of the effects of the acute administration of dexoxadrol, levoxadrol, MK-801 and phencyclidine on body temperature in the rat. Pechnick, R.N., Wong, C.A., George, R., Thurkauf, A., Jacobson, A.E., Rice, K.C. Neuropharmacology (1989)
- High efficiency reconstitution of a phencyclidine/MK-801 receptor binding site solubilized from rat forebrain membranes. Haring, R., Pellegrini-Giampietro, D.E., Zukin, S.R., Zukin, R.S., Scheideler, M.A. Mol. Pharmacol. (1991)
- A phencyclidine recognition site is associated with N-methyl-D-aspartate inhibition of carbachol-stimulated phosphoinositide hydrolysis in rat cortical slices. Gonzales, R.A., Moerschbaecher, J.M. Mol. Pharmacol. (1989)
- Analogues of the dioxolanes dexoxadrol and etoxadrol as potential phencyclidine-like agents. Synthesis and structure-activity relationships. Thurkauf, A., Mattson, M.V., Richardson, S., Mirsadeghi, S., Ornstein, P.L., Harrison, E.A., Rice, K.C., Jacobson, A.E., Monn, J.A. J. Med. Chem. (1992)
- Phencyclidine suppresses hippocampal long-term potentiation through stereospecific activation of phencyclidine receptors. Bourne, G.W., Capek, R., Esplin, B. Neuropharmacology (1989)
- Enantiomeric and diastereomeric dioxadrols: behavioral, biochemical and chemical determination of the configuration necessary for phencyclidine-like properties. Jacobson, A.E., Harrison, E.A., Mattson, M.V., Rafferty, M.F., Rice, K.C., Woods, J.H., Winger, G., Solomon, R.E., Lessor, R.A., Silverton, J.V. J. Pharmacol. Exp. Ther. (1987)
- Regional heterogeneity of rat brain phencyclidine (PCP) receptors revealed by photoaffinity labeling with [3H] azido phencyclidine. Haring, R., Kloog, Y., Sokolovsky, M. Biochem. Biophys. Res. Commun. (1985)
- Stereospecific binding of 3H-phencyclidine in brain membranes. Hampton, R.Y., Medzihradsky, F., Woods, J.H., Dahlstrom, P.J. Life Sci. (1982)
- A comparison of PCP-like compounds for NMDA antagonism in two in vivo models. Bennett, D.A., Bernard, P.S., Amrick, C.L. Life Sci. (1988)
- Structure-affinity relationship studies of non-competitive NMDA receptor antagonists derived from dexoxadrol and etoxadrol. Aepkers, M., Wünsch, B. Bioorg. Med. Chem. (2005)
- Molecular modeling of noncompetitive antagonists of the NMDA receptor: proposal of a pharmacophore and a description of the interaction mode. Elhallaoui, M., Laguerre, M., Carpy, A., Ouazzani, F.C. Journal of molecular modeling (Online) (2002)