Disease relevance of Clinitest

• Infants were chosen who had sustained hyperglycemia (150 mg/dl) and glucosuria (2+ Clinitest) requiring glucose infusion at a rate below 7 mg/kg/minute for more than 24 hours [1].
• Five children developed esophageal stricture from the ingestion of a Clinitest tablet [2].
• Clinitest tablets produced distal esophagitis and stricture and antral damage leading to gastric outlet obstruction which required operative intervention [3].
• In a laboratory, students a) determined blood pressures on six videotaped subjects, b) graded sugar content of unknown solutions from 0 to 4+ using Clinitest tablets, c) measured papules that simulated PPD reactions, d) measured heart and kidney size on X-rays and, e) described a model skin lesion (melanoma) [4].
• The 2-drop Clinitest method detects glycosuria up to 5% without significant loss of accuracy and is recommended in preference to the 5-drop method [5].

High impact information on Clinitest

• Isoniazid has been shown by in vitro study to reduce Clinitest tablets [6].
• In method comparison on patients' samples, Chemstrip uG was significantly stronger in its association with the quantitative hexokinase method than was Diastix, Clinitest, or Tes-Tape [7].
• Clinitest burns of the esophagus [2].
• Because the Clinitest-penicillin interaction is unpredictable, Clinitest results should be rechecked using one of the qualitative glucose oxidase tests when Clinitest is used as a quantitative test for glycosuria in patients receiving penicillins [8].
• Clinical features characteristic of rotavirus-associated cases included: dehydration and acidosis upon admission, vomiting, fever, neutropenia and sugar in the stools (Clinitest greater than or equal to 0.5%) [9].

Analytical, diagnostic and therapeutic context of Clinitest

• The methods used were the Clinitest method and paper chromatography [10].

References