Disease relevance of Esophageal Stenosis

• CONTEXT: Severe gastroesophageal reflux disease (GERD) is a lifelong problem that can be complicated by peptic esophageal stricture and adenocarcinoma of the esophagus [1].
• Risk factors for BE include conditions that are associated with GER such as mental retardation, esophageal stricture, esophageal atresia, and reversed gastric tube esophagoplasty [2].
• MATERIALS AND METHODS: One hundred patients with severe dysphagia secondary to malignant esophageal strictures were treated with self-expanding nitinol stents [3].
• Glutaraldehyde-induced esophageal injury should therefore be considered in patients who develop esophagitis or esophageal strictures after upper endoscopy [4].
• OBJECTIVES: We sought to determine whether treatment with montelukast would improve symptoms and decrease both peripheral blood and tissue eosinophilia (TE) in a patients with steroid-dependent EG for 20 years complicated by esophageal stricture [5].

High impact information on Esophageal Stenosis

• BACKGROUND/AIMS: Dilatation combined with subsequent pharmacological control of gastroesophageal reflux represents a logical but poorly documented approach to the management of benign esophageal stricture [6].
• A comparison of omeprazole and ranitidine in the prevention of recurrence of benign esophageal stricture. Restore Investigator Group [6].
• Esophageal stricture associated with alendronate therapy [7].
• In one patient receiving cimetidine, distal esophageal stenosis developed, requiring dilatation therapy [8].
• Esophagogastrectomy for benign esophageal stricture. Fate of the esophagogastric anastomosis [9].

Chemical compound and disease context of Esophageal Stenosis

• Covered retrievable expandable nitinol stents in patients with benign esophageal strictures: initial experience [10].
• PURPOSE: To evaluate the clinical effectiveness of a polyurethane-covered, retrievable, self-expandable metallic stent and hook catheter in the treatment of esophageal strictures [11].
• CONCLUSIONS: In patients with recalcitrant peptic esophageal stricture, steroid injection into the stricture combined with acid suppression significantly diminishes both the need for repeat dilation and the average time to repeat dilation compared to sham injection and acid suppression alone [12].
• Usefulness of intralesional triamcinolone in treatment of benign esophageal strictures [13].
• CONCLUSIONS: Halofuginone, a specific inhibitor of collagen type 1 synthesis, significantly reduced esophageal stricture occurrence [14].

Anatomical context of Esophageal Stenosis

• Tubular esophageal duplication associated with esophageal stenosis, pericardial aplasia, diaphragmatic hernia, ramification anomaly of lower lobe bronchus and partial pancreas anulare [15].

Gene context of Esophageal Stenosis

• RESULTS: In MEN1/ZES patients, esophageal stricture was 3-fold higher, BE 5-fold higher, and dysplasia 8-fold higher, and one patient died of esophageal adenocarcinoma [16].
• Barium esophagram revealed distal esophageal stenosis and subsequently an H-type TEF at surgery [17].
• METHODS: Adults undergoing outpatient bougienage for a benign or malignant esophageal stricture were randomized in a clinician-blinded fashion to either pre-procedure clindamycin mouthwash or no treatment [18].
• Effects of caffeic acid phenethyl ester and epidermal growth factor on the development of caustic esophageal stricture in rats [19].
• There is an association between esophageal stricture and ASA/NSAID use, which includes OTC NSAIDs and low-dose ASA [20].

Analytical, diagnostic and therapeutic context of Esophageal Stenosis

• CONCLUSION: Intralesional injections of triamcinolone augment the effects of dilation in patients with benign esophageal strictures [13].
• Role of endoscopic ultrasonography in guiding intralesional steroid injections in esophageal strictures [21].
• We evaluated the computer tomography (CT) scan, technetium-99m-methylene diphosphonate bone scan and positron emission tomography with 2-[18F]-fluoro-2-deoxy-D-glucose (FDG-PET) findings of ICMF and the frequency of airway or esophageal stenosis [22].
• Gastroesophageal reflux and achalasia are important differential diagnoses of esophageal stenosis, they may be associated with CES making appropriate management even more difficult [23].

References