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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Perimed     1-ethenylpyrrolidin-2-one; hydrogen...

Synonyms: AC1MIW7L, 113813-79-9
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Disease relevance of Perimed


High impact information on Perimed


Biological context of Perimed


Anatomical context of Perimed

  • Erythematous responses were assessed visually and skin blood flow determined by means of a laser Doppler flow meter which measures the blood cell flux (Pf2 Perimed, Sweden) [9].

Associations of Perimed with other chemical compounds

  • The effect of treatment was compared with untreated skin and evaluated in terms of (a) O2-consumption as measured by the TCM-2-oxygen monitor from Radiometer, Denmark, (b) blood flow as measured by a laser-Doppler flowmeter (Perimed, Sweden), (c) temperature measurements using thermo-couples and (d) a clinical score [10].

Analytical, diagnostic and therapeutic context of Perimed

  • The microvascular blood flow of the parietal cortex on the right or on both sides was continuously recorded by the laser-Doppler flowmeter (Periflux PF2B, Perimed, Stockholm, Sweden) [11].
  • The instrument used was a Laser Doppler Perfusion Monitor, Pf3 (Perimed, Stockholm, Sweden) [12].
  • MAIN OUTCOME MEASUREMENTS: Cortical bone blood flow was assessed by laser Doppler flowmetry using a standard metalshafted probe (Periflux Pf303, Perimed, Jarfalla, Sweden) applied through holes in the custom-made LCDCPs at five sites [13].
  • It was concluded that the use of Perimed could be a beneficial adjunctive treatment for the prevention and control of gingivitis when used with routine oral hygiene procedures [1].


  1. Efficacy of Perimed antibacterial system on established gingivitis. (I). Clinical results. Clark, W.B., Magnusson, I., Walker, C.B., Marks, R.G. Journal of clinical periodontology. (1989) [Pubmed]
  2. ATP-induced cochlear blood flow changes involve the nitric oxide pathway. Ren, T., Nuttall, A.L., Miller, J.M. Hear. Res. (1997) [Pubmed]
  3. Adrenergic supersensitivity of rabbit choroidal blood vessels after sympathetic denervation. Chou, P.I., Lu, D.W., Chen, J.T. Curr. Eye Res. (2001) [Pubmed]
  4. In vivo monitoring of circulation in the intact anterior cruciate ligament using the laser Doppler flowmeter. Passler, J.M., Wildburger, R., Hofer, H.P., Fellinger, M. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. (1993) [Pubmed]
  5. Topographic mapping of the cutaneous microcirculation using two outputs of laser-Doppler flowmetry: flux and the concentration of moving blood cells. Braverman, I.M., Schechner, J.S., Silverman, D.G., Keh-Yen, A. Microvasc. Res. (1992) [Pubmed]
  6. The effect of 3 mouthrinses on plaque and gingivitis development. Maruniak, J., Clark, W.B., Walker, C.B., Magnusson, I., Marks, R.G., Taylor, M., Clouser, B. Journal of clinical periodontology. (1992) [Pubmed]
  7. Inhibition of leukocyte-endothelial adherence following thermal injury. Mileski, W., Borgstrom, D., Lightfoot, E., Rothlein, R., Faanes, R., Lipsky, P., Baxter, C. J. Surg. Res. (1992) [Pubmed]
  8. Effect of sympathetic denervation on rabbit choroidal blood flow. Chou, P.I., Lu, D.W., Chen, J.T. Ophthalmologica (2002) [Pubmed]
  9. Hexyl-nicotinate-induced vasodilation in normal human skin. Dowd, P.M., Whitefield, M., Greaves, M.W. Dermatologica (1987) [Pubmed]
  10. Antipsoriatic effect of local corticosteroids--O2-consumption and blood flow measurements compared to clinical parameters. Broby-Johansen, U., Kristensen, J.K. Clin. Exp. Dermatol. (1989) [Pubmed]
  11. Vasomotion in the rat cerebral microcirculation recorded by laser-Doppler flowmetry. Morita-Tsuzuki, Y., Bouskela, E., Hardebo, J.E. Acta Physiol. Scand. (1992) [Pubmed]
  12. The response of skin microcirculation to hyperthermic stress in tumour patients. Ranade, G.G., Puniyani, R.R., Huilgol, N.G. Clinical physiology (Oxford, England) (1995) [Pubmed]
  13. Effect of stainless steel and titanium low-contact dynamic compression plate application on the vascularity and mechanical properties of cortical bone after fracture. Jain, R., Podworny, N., Hearn, T., Anderson, G.I., Schemitsch, E.H. Journal of orthopaedic trauma. (1997) [Pubmed]
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