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Disease relevance of Arthroscopy


High impact information on Arthroscopy

  • In 13 patients with RA and 19 patients with various other rheumatological disorders, knee ST biopsies were collected in macroscopically inflamed areas identified under arthroscopy [6].
  • METHODS: Ten patients with PsA (median duration 18 months) underwent arthroscopy and synovial biopsy of an inflamed knee before and after clinical improvement induced by methotrexate [7].
  • METHODS: Leptin levels in SF samples obtained from OA patients undergoing either knee replacement surgery or knee arthroscopy were measured by enzyme-linked immunosorbent assay [8].
  • METHODS: Hematoxylin and eosin staining and histologic grading for inflammation were performed for 104 patients who met the American College of Rheumatology criteria for OA and had undergone total joint replacement or arthroscopy [9].
  • RESULTS: Diacerhein treatment slowed the progression of OA, as measured by grading of gross changes in the unstable knee at arthroscopy 16 weeks after cruciate ligament transection (P = 0.04) and at the time the animals were killed, 32 weeks after surgery (P = 0.05) [10].

Chemical compound and disease context of Arthroscopy


Biological context of Arthroscopy

  • We think that adding epinephrine to only portal site injections is sufficient to obtain a clear view and, furthermore, when carrying out arthroscopy in this manner, no significant changes are encountered in heart rate, mean arterial pressure, pain during arthroscopy, or time of arthroscopy [16].
  • Our findings thus demonstrate that MRI is more sensitive than arthroscopy in the detection of intrasubstance pathologies of the lateral discoid menisci [17].
  • We evaluated bacterial density and composition on the skin of 15 patients undergoing knee arthroscopy and the left hand of two surgeons after standard disinfection with povidone-iodine [18].
  • At 10 days' follow-up, in patients who had undergone operative arthroscopy naproxen sodium demonstrated a statistically significant effect on synovial effusion (p < 0.01), range of motion (p < 0.001), quadriceps strength (p < 0.05), pain (p < 0.001), walking activity (p < 0.05), and use of crutches (p < 0.01) [19].
  • CONCLUSION: The auditory evoked potential index provided by the A-line monitor does not decrease sevoflurane consumption or emergence times for ambulatory knee arthroscopy [20].

Anatomical context of Arthroscopy


Associations of Arthroscopy with chemical compounds


Gene context of Arthroscopy

  • In 20 knee samples of series I of patients who received arthroscopy (series II), we examined the amounts of MMP-2 and 9 in effusions and serial synovial organ cultures [31].
  • MATERIALS AND METHODS: Synovial specimens obtained from patients with ID (31 patients), osteoarthritis (11 patients), and condylar fractures of the mandible (5 patients) during arthroscopy were examined immunohistochemically using antibodies against CD68, inducible nitric oxide synthase (iNOS), Fas, and single-stranded DNA (ssDNA) [32].
  • METHODS: Synovial biopsy specimens were obtained by arthroscopy from patients with RA and disease controls for immunohistological analysis using a monoclonal antibody specific for IFNbeta [33].
  • All 18 of these patients were clinically suspected of having meniscal damage; however, only partial and complete ACL tears were found at arthroscopy [34].
  • Arthroscopy was performed using the anterior midline approach [35].

Analytical, diagnostic and therapeutic context of Arthroscopy


  1. Distinct vascular patterns of early synovitis in psoriatic, reactive, and rheumatoid arthritis. Reece, R.J., Canete, J.D., Parsons, W.J., Emery, P., Veale, D.J. Arthritis Rheum. (1999) [Pubmed]
  2. Specific presence of intracellular citrullinated proteins in rheumatoid arthritis synovium: relevance to antifilaggrin autoantibodies. Baeten, D., Peene, I., Union, A., Meheus, L., Sebbag, M., Serre, G., Veys, E.M., De Keyser, F. Arthritis Rheum. (2001) [Pubmed]
  3. Turnover of type II collagen and aggrecan in cartilage matrix at the onset of inflammatory arthritis in humans: relationship to mediators of systemic and local inflammation. Fraser, A., Fearon, U., Billinghurst, R.C., Ionescu, M., Reece, R., Barwick, T., Emery, P., Poole, A.R., Veale, D.J. Arthritis Rheum. (2003) [Pubmed]
  4. Dilution of spinal lidocaine does not alter the incidence of transient neurologic symptoms. Pollock, J.E., Liu, S.S., Neal, J.M., Stephenson, C.A. Anesthesiology (1999) [Pubmed]
  5. Treatment of pigmented villonodular synovitis of the knee with yttrium-90 silicate: prospective evaluations by arthroscopy, histology, and 99mTc pertechnetate uptake measurements. Franssen, M.J., Boerbooms, A.M., Karthaus, R.P., Buijs, W.C., van de Putte, L.B. Ann. Rheum. Dis. (1989) [Pubmed]
  6. Fibrin deimination in synovial tissue is not specific for rheumatoid arthritis but commonly occurs during synovitides. Chapuy-Regaud, S., Sebbag, M., Baeten, D., Clavel, C., Foulquier, C., De Keyser, F., Serre, G. J. Immunol. (2005) [Pubmed]
  7. Reduction of synovial sublining layer inflammation and proinflammatory cytokine expression in psoriatic arthritis treated with methotrexate. Kane, D., Gogarty, M., O'leary, J., Silva, I., Bermingham, N., Bresnihan, B., Fitzgerald, O. Arthritis Rheum. (2004) [Pubmed]
  8. Evidence for a key role of leptin in osteoarthritis. Dumond, H., Presle, N., Terlain, B., Mainard, D., Loeuille, D., Netter, P., Pottie, P. Arthritis Rheum. (2003) [Pubmed]
  9. Inflammation and angiogenesis in osteoarthritis. Haywood, L., McWilliams, D.F., Pearson, C.I., Gill, S.E., Ganesan, A., Wilson, D., Walsh, D.A. Arthritis Rheum. (2003) [Pubmed]
  10. Diacerhein treatment reduces the severity of osteoarthritis in the canine cruciate-deficiency model of osteoarthritis. Smith, G.N., Myers, S.L., Brandt, K.D., Mickler, E.A., Albrecht, M.E. Arthritis Rheum. (1999) [Pubmed]
  11. Intraarticular analgesia following knee arthroscopy. Joshi, G.P., McCarroll, S.M., O'Brien, T.M., Lenane, P. Anesth. Analg. (1993) [Pubmed]
  12. Postoperative pain following knee arthroscopy: the effects of intra-articular ketorolac and/or morphine. Gupta, A., Axelsson, K., Allvin, R., Liszka-Hackzell, J., Rawal, N., Althoff, B., Augustini, B.G. Regional anesthesia and pain medicine. (1999) [Pubmed]
  13. Intra-articular tenoxicam improves postoperative analgesia in knee arthroscopy. Colbert, S.T., Curran, E., O'Hanlon, D.M., Moran, R., McCarroll, M. Canadian journal of anaesthesia = Journal canadien d'anesthésie. (1999) [Pubmed]
  14. Quantitative electroencephalographic evaluation to determine the quality of analgesia during anesthesia of horses for arthroscopic surgery. Miller, S.M., Short, C.E., Ekström, P.M. Am. J. Vet. Res. (1995) [Pubmed]
  15. Arthroscopic treatment of steroid-induced osteonecrosis of the humeral head. Hayes, J.M. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. (1989) [Pubmed]
  16. Effects of epinephrine in local anesthetic mixtures on hemodynamics and view quality during knee arthroscopy. Karaoglu, S., Dogru, K., Kabak, S., Inan, M., Halici, M. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. (2002) [Pubmed]
  17. Usefulness of magnetic resonance imaging for detecting intrasubstance tear and/or degeneration of lateral discoid meniscus. Hamada, M., Shino, K., Kawano, K., Araki, Y., Matsui, Y., Doi, T. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. (1994) [Pubmed]
  18. Are surgical scrubbing and pre-operative disinfection of the skin in orthopaedic surgery reliable? Salvi, M., Chelo, C., Caputo, F., Conte, M., Fontana, C., Peddis, G., Velluti, C. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. (2006) [Pubmed]
  19. The clinical effect of naproxen sodium after arthroscopy of the knee: a randomized, double-blind, prospective study. Rasmussen, S., Thomsen, S., Madsen, S.N., Rasmussen, P.J., Simonsen, O.H. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. (1993) [Pubmed]
  20. Sevoflurane requirements during ambulatory surgery: a clinical study with and without AEP-index guidance. Assareh, H., Anderson, R.E., Uusijärvi, J., Jakobsson, J. Acta anaesthesiologica Scandinavica. (2002) [Pubmed]
  21. Augmented interleukin-1 production and HLA-DR expression in the synovium of rheumatoid arthritis patients. Possible involvement in joint destruction. Miyasaka, N., Sato, K., Goto, M., Sasano, M., Natsuyama, M., Inoue, K., Nishioka, K. Arthritis Rheum. (1988) [Pubmed]
  22. Low-dose intra-articular morphine analgesia in day case knee arthroscopy: a randomized double-blinded prospective study. Dalsgaard, J., Felsby, S., Juelsgaard, P., Froekjaer, J. Pain (1994) [Pubmed]
  23. Superoxide dismutase isoenzymes of the synovial fluid in rheumatoid arthritis and in reactive arthritides. Marklund, S.L., Bjelle, A., Elmqvist, L.G. Ann. Rheum. Dis. (1986) [Pubmed]
  24. The discoid lateral-meniscus syndrome. Dickhaut, S.C., DeLee, J.C. The Journal of bone and joint surgery. American volume. (1982) [Pubmed]
  25. Intraarticular tophi in a joint without a previous gouty attack. Yu, K.H. J. Rheumatol. (2003) [Pubmed]
  26. Discoid menisci of the knee: MR imaging appearance. Silverman, J.M., Mink, J.H., Deutsch, A.L. Radiology. (1989) [Pubmed]
  27. A comparison of 50, 100 and 200 mg of intra-articular pethidine during knee joint surgery, a controlled study with evidence for local demethylation to norpethidine. Söderlund, A., Boreus, L.O., Westman, L., Engström, B., Valentin, A., Ekblom, A. Pain (1999) [Pubmed]
  28. Labral-ligamentous complex of the shoulder: evaluation with MR arthrography. Palmer, W.E., Brown, J.H., Rosenthal, D.I. Radiology. (1994) [Pubmed]
  29. Postarthroscopy analgesia with intraarticular bupivacaine/morphine. A randomized clinical trial. Allen, G.C., St Amand, M.A., Lui, A.C., Johnson, D.H., Lindsay, M.P. Anesthesiology (1993) [Pubmed]
  30. Combined spinal-epidural anesthesia for outpatient surgery. Dose-response characteristics of intrathecal isobaric lidocaine using a 27-gauge Whitacre spinal needle. Urmey, W.F., Stanton, J., Peterson, M., Sharrock, N.E. Anesthesiology (1995) [Pubmed]
  31. The significance of altered gelatinase expression in the synovium of patient with arthritic effusions. Lu, K.H., Yang, S.F., Chu, S.C., Chen, P.N., Chou, M.C., Hsiao, T.Y., Hsieh, Y.S. Clin. Rheumatol. (2004) [Pubmed]
  32. Inducible nitric oxide synthase and apoptosis-related factors in the synovial tissues of temporomandibular joints with internal derangement and osteoarthritis. Nagai, H., Kumamoto, H., Fukuda, M., Takahashi, T. J. Oral Maxillofac. Surg. (2003) [Pubmed]
  33. Expression of interferon beta in synovial tissue from patients with rheumatoid arthritis: comparison with patients with osteoarthritis and reactive arthritis. van Holten, J., Smeets, T.J., Blankert, P., Tak, P.P. Ann. Rheum. Dis. (2005) [Pubmed]
  34. Fat pad adhesion to partially torn anterior cruciate ligament: a cause of knee locking. Finsterbush, A., Frankl, U., Mann, G. The American journal of sports medicine. (1989) [Pubmed]
  35. Arthroscopic meniscectomy in athletes. Lysholm, J., Gillquist, J. The American journal of sports medicine. (1983) [Pubmed]
  36. Postoperative analgesia by intra-articular neostigmine in patients undergoing knee arthroscopy. Yang, L.C., Chen, L.M., Wang, C.J., Buerkle, H. Anesthesiology (1998) [Pubmed]
  37. Transient neurologic symptoms after spinal anesthesia with mepivacaine and lidocaine. Liguori, G.A., Zayas, V.M., Chisholm, M.F. Anesthesiology (1998) [Pubmed]
  38. A randomized placebo-controlled trial of arthroscopic lavage versus lavage plus intra-articular corticosteroids in the management of symptomatic osteoarthritis of the knee. Smith, M.D., Wetherall, M., Darby, T., Esterman, A., Slavotinek, J., Roberts-Thomson, P., Coleman, M., Ahern, M.J. Rheumatology (Oxford, England) (2003) [Pubmed]
  39. Possible bupivacaine toxicity after intraarticular injection for postarthroscopic analgesia of the knee: implications of the surgical procedure. Liguori, G.A., Chimento, G.F., Borow, L., Figgie, M. Anesth. Analg. (2002) [Pubmed]
  40. Lidocaine local anesthesia for arthroscopic knee surgery. Dahl, M.R., Dasta, J.F., Zuelzer, W., McSweeney, T.D. Anesth. Analg. (1990) [Pubmed]
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