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Chemical Compound Review

Tecoflex     4-[[4-[[4- (butoxycarbonylamino) cyclohexyl]...

Synonyms: AC1Q2WMP, AC1MJ5IG, 76600-67-4
 
 
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High impact information on Tecoflex

  • A more marked decrease in platelet adhesion is, however, observed when the Tecoflex-based membranes are coated with a thin photo-cross-linked layer of poly(ethylene oxide) [1].
  • The results suggest that three-dimensionally porous, Tecoflex-derived elastic biomaterials may be suitable substrates for engineering vocal fold tissue [2].
  • A combination of cryomicrotomy and transmission Fourier transform infrared (FTIR) microscopy was used to investigate chemical changes in unstrained sheets of Pellethane 2363-80A, Tecoflex EG80A and Biomer caused by biodegradation (18 month subcutaneous ovine implant) [3].
  • An aliphatic polyether based polyurethane, Tecoflex (TF; Thermedics, Inc., Woburn, MA), is used in the construction of a proprietary peritoneal dialysis (PD) catheter [4].
  • PC-DLC demonstrated that Tecoflex showed higher complement activation than PC-DLC [5].
 

Biological context of Tecoflex

  • Myoblasts attached, proliferated, displayed migratory activity and differentiated into multinucleated myotubes which expressed myosin heavy chain on solid thin films indicating that Tecoflex SG-80A was permissive for skeletal myogenesis [6].
 

Anatomical context of Tecoflex

 

Associations of Tecoflex with other chemical compounds

 

Gene context of Tecoflex

  • The authors selected two PCUs, Corethane 80A (Corvita Corporation, Miami, FL) and PCU(1560), and two PEUs, Pellethene 2363-80AE (Dow Chemical Japan, Tokyo, Japan) and Tecoflex EG80A (Thermedics, Inc., Woburn, MA), all of which have similar hard segment compositions (MDI or HMDI:1,4-butanediol(BD)) and the same hardness of 80A [9].
 

Analytical, diagnostic and therapeutic context of Tecoflex

  • This was less pronounced when stents coated with Tecoflex (Advanced Surgical Intervention Co., San Clemente, Calif.) were used [10].
  • Based on our TECOFLEX materials technology, the dressing performs like temporary artificial skin [11].
  • An organotypic culture assay has been used to assess the biocompatibility and cytotoxicity of an arterial prosthesis developed at the University of Texas-Arlington (the UTA graft) from a structurally modified polyurethane (PU) elastomer (Tecoflex) [12].

References

  1. Thrombogenic properties of untreated and poly(ethylene oxide)-modified polymeric matrices useful for preparing intraarterial ion-selective electrodes. Espadas-Torre, C., Meyerhoff, M.E. Anal. Chem. (1995) [Pubmed]
  2. Comparison of human fibroblast ECM-related gene expression on elastic three-dimensional substrates relative to two-dimensional films of the same material. Webb, K., Li, W., Hitchcock, R.W., Smeal, R.M., Gray, S.D., Tresco, P.A. Biomaterials (2003) [Pubmed]
  3. In-vivo degradation of polyurethanes: transmission-FTIR microscopic characterization of polyurethanes sectioned by cryomicrotomy. McCarthy, S.J., Meijs, G.F., Mitchell, N., Gunatillake, P.A., Heath, G., Brandwood, A., Schindhelm, K. Biomaterials (1997) [Pubmed]
  4. Clinical biodurability of aliphatic polyether based polyurethanes as peritoneal dialysis catheters. Crabtree, J.H. ASAIO journal (American Society for Artificial Internal Organs : 1992) (2003) [Pubmed]
  5. Improved blood compatibility of DLC coated polymeric material. Alanazi, A., Nojiri, C., Noguchi, T., Kido, T., Komatsu, Y., Hirakuri, K., Funakubo, A., Sakai, K., Fukui, Y. ASAIO journal (American Society for Artificial Internal Organs : 1992) (2000) [Pubmed]
  6. Skeletal myogenesis on elastomeric substrates: implications for tissue engineering. Mulder, M.M., Hitchcock, R.W., Tresco, P.A. Journal of biomaterials science. Polymer edition. (1998) [Pubmed]
  7. Replacement of the os trapezium by polyurethane implants. Sollerman, C., Hasselgren, G., Westermark, J., Herrlin, K. Scandinavian journal of plastic and reconstructive surgery and hand surgery / Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi. (1993) [Pubmed]
  8. Cell seeding on microporous and solid polyurethane. Sendler, S., Schauwecker, H.H., Bücherl, E.S. Life support systems : the journal of the European Society for Artificial Organs. (1987) [Pubmed]
  9. Comparative blood compatibility of polyether vs polycarbonate urethanes by epifluorescent video microscopy. Mizumoto, D., Nojiri, C., Inomata, Y., Onishi, M., Waki, M., Kido, T., Sugiyama, T., Senshu, K., Uchida, K., Sakai, K., Akutsu, T. ASAIO journal (American Society for Artificial Internal Organs : 1992) (1997) [Pubmed]
  10. Endoscopically introduced expandable stents in laryngotracheal stenosis: the jury is still out. Hanna, E., Eliachar, I. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. (1997) [Pubmed]
  11. Spandra: a sustained release battlefield wound dressing. Szycher, M., Setterstrom, J.A., Vincent, J.W., Battistone, G. Journal of biomaterials applications. (1986) [Pubmed]
  12. A novel microporous polyurethane blood conduit: biocompatibility assessment of the UTA arterial prosthesis by an organo-typic culture technique. Sigot-Luizard, M.F., Sigot, M., Guidoin, R., King, M., von Maltzahn, W.W., Kowligi, R., Eberhart, R.C. Journal of investigative surgery : the official journal of the Academy of Surgical Research. (1993) [Pubmed]
 
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