The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

AC1L9DDB     2,3-dimethyl-5- (3,7,11,14,19,23,27,31,35...

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Plastoquinone-9

  • A photosystem I (PS I) complex containing plastoquinone-9 (PQ-9) but devoid of F(X), F(B), and F(A) was isolated and characterized from a mutant strain of Synechococcus sp. PCC 7002 in which the menB and rubA genes were insertionally inactivated [1].
  • Plastoquinone-9 (PQ-9) depleted PSII reaction center core complex consisting of D1, D2, CP47, cytochrome b-559 (cyt b-559), PSII-I and PSII-W was reconstituted with PQ-9 and digalactosyldiglyceride (DGDG) together with the wild-type or mutant PSII-L produced in E. coli or isolated PSII-L from spinach [2].

High impact information on Plastoquinone-9

  • HPLC analyses show high levels of plastoquinone-9 in PS I complexes from the menA and menB mutants but not from the wild type [3].
  • By subtracting the known (3)P700 spectral signatures, we produce an A(1)(-)/A(1) FTIR difference spectrum for PS I particles with plastoquinone-9 occupying the binding site [4].
  • Plastoquinol-9 formed in thylakoids as a result of enzymatic reduction of plastoquinone-9 by ferredoxin-plastoquinone reductase was even more active than the externally added plastoquinol-9 in the investigated reaction [5].
  • A modeling of the forward and backward electron transfer kinetics in P700-F(A)/F(B) complexes, P700-F(X) cores, and P700-A(1) cores shows that the replacement of phylloquinone by plastoquinone-9 induces a decrease in the free energy gap between A(1) and F(A)/F(B) from approximately -205 mV in wild-type PS I to approximately -70 mV in menA PS I [6].
  • Modeling of the P700+ charge recombination kinetics with phylloquinone and plastoquinone-9 in the A1 site of photosystem I [6].

Biological context of Plastoquinone-9


Anatomical context of Plastoquinone-9

  • We have studied the incorporation of chlorophyll a and plastoquinone-9 in Montal-Mueller membranes [7].
  • In Scenedesmus obliquus not only all plastid isoprenoids (carotenoids and prenyl side chains of chlorophylls and plastoquinone-9) were formed via this novel pathway, but also the non-plastid cytoplasmic sterols [8].

Associations of Plastoquinone-9 with other chemical compounds

  • Treatment of such samples (referred to as iron-depleted) with sodium dithionite or illumination in the presence of dichlorophenol indophenol (DCIP) and sodium ascorbate yielded EPR spectra similar to those of the plastoquinone-9 (PQ-9) radical anion generated in organic solvents [9].
  • A convenient and precise method for the separation and determination of coenzyme Q (CoQ)-related compounds (CoQ homologues, plastoquinone-9, ubichromenol-9, etc.) was developed using high-performance liquid chromatography (HPLC) [10].
  • The efficiency of oxidized endogenous plastoquinone-9 (PQ-9) as a non-photochemical quencher of chlorophyll fluorescence has been analyzed in spinach thylakoids and PS II membrane fragments isolated by Triton X-100 fractionation of grana stacks [11].

Analytical, diagnostic and therapeutic context of Plastoquinone-9


  1. Recruitment of a foreign quinone into the A1 site of photosystem I. Characterization of a menB rubA double deletion mutant in Synechococcus sp. PCC 7002 devoid of FX, FA, and FB and containing plastoquinone or exchanged 9,10-anthraquinone. Sakuragi, Y., Zybailov, B., Shen, G., Bryant, D.A., Golbeck, J.H., Diner, B.A., Karygina, I., Pushkar, Y., Stehlik, D. J. Biol. Chem. (2005) [Pubmed]
  2. Role of PSII-L protein (psbL gene product) on the electron transfer in photosystem II complex. 1. Over-production of wild-type and mutant versions of PSII-L protein and reconstitution into the PSII core complex. Ozawa, S., Kobayashi, T., Sugiyama, R., Hoshida, H., Shiina, T., Toyoshima, Y. Plant Mol. Biol. (1997) [Pubmed]
  3. Recruitment of a foreign quinone into the A(1) site of photosystem I. I. Genetic and physiological characterization of phylloquinone biosynthetic pathway mutants in Synechocystis sp. pcc 6803. Johnson, T.W., Shen, G., Zybailov, B., Kolling, D., Reategui, R., Beauparlant, S., Vassiliev, I.R., Bryant, D.A., Jones, A.D., Golbeck, J.H., Chitnis, P.R. J. Biol. Chem. (2000) [Pubmed]
  4. Time-Resolved FTIR Difference Spectroscopy for the Study of Photosystem I Particles with Plastoquinone-9 Occupying the A(1) Binding Site. Bandaranayake, K.M., Wang, R., Johnson, T.W., Hastings, G. Biochemistry (2006) [Pubmed]
  5. Scavenging of superoxide generated in photosystem I by plastoquinol and other prenyllipids in thylakoid membranes. Kruk, J., Jemioła-Rzemińska, M., Burda, K., Schmid, G.H., Strzałka, K. Biochemistry (2003) [Pubmed]
  6. Modeling of the P700+ charge recombination kinetics with phylloquinone and plastoquinone-9 in the A1 site of photosystem I. Shinkarev, V.P., Zybailov, B., Vassiliev, I.R., Golbeck, J.H. Biophys. J. (2002) [Pubmed]
  7. The electrical and spectroscopic properties of planar asymmetrical membranes incorporating chlorophyll a and plastoquinone-9. Model of incorporation of chlorophyll a and plastoquinone-9. Robert, S., Tancrède, P. Biochem. Cell Biol. (1991) [Pubmed]
  8. A new alternative non-mevalonate pathway for isoprenoid biosynthesis in eubacteria and plants. Paseshnichenko, V.A. Biochemistry Mosc. (1998) [Pubmed]
  9. EPR and ENDOR investigation of the primary electron acceptor radical anion QA.- in iron-depleted photosystem II membrane fragments. MacMillan, F., Lendzian, F., Renger, G., Lubitz, W. Biochemistry (1995) [Pubmed]
  10. High-performance liquid chromatography of coenzyme Q-related compounds and its application to biological materials. Okamoto, T., Fukui, K., Nakamoto, M., Kishi, T., Okishio, T., Yamagami, T., Kanamori, N., Kishi, H., Hiraoka, E. J. Chromatogr. (1985) [Pubmed]
  11. Investigation of the plastoquinone pool size and fluorescence quenching in thylakoid membranes and Photosystem II (PS II) membrane fragments. Kurreck, J., Schödel, R., Renger, G. Photosyn. Res. (2000) [Pubmed]
WikiGenes - Universities