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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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Disease relevance of Scenedesmus


High impact information on Scenedesmus

  • The results of ultrastructural studies and transmission electron microscope microanalysis of two Scenedesmus strains experimentally exposed to copper sulfate are presented [6].
  • Because tocopherol-deficient mutants in the green alga Scenedesmus obliquus can synthesize carotenoids, our findings demonstrate conclusively that plastoquinone is an essential component in carotenoid synthesis [7].
  • The LF-1 mutant strain of Scenedesmus (isolated by Dr. Norman Bishop) is incapable of processing pre-D1 [8].
  • Photoinactivation and light-dependent degradation of the D1 protein were drastically increased in the Scenedesmus obliquus LF-1 mutant cells altered in its PSII manganese binding and thus unable to reduce PQ using water as an electron donor [9].
  • The mitochondrial group IIB intron rI1, from the green algae Scenedesmus obliquus ' LSUrRNA gene, has been introduced into the lacZ gene encoding beta-galacto-sidase [10].

Chemical compound and disease context of Scenedesmus


Biological context of Scenedesmus


Anatomical context of Scenedesmus

  • Adenine inhibition of the synthesis of photosynthetic membranes in the chloroplast of Scenedesmus obliquus grown in the dark [21].
  • In Scenedesmus obliquus not only all plastid isoprenoids (carotenoids and prenyl side chains of chlorophylls and plastoquinone-9) were formed via this novel pathway, but also the non-plastid cytoplasmic sterols [22].

Associations of Scenedesmus with chemical compounds

  • Isoprenoid biosynthesis was investigated in the green alga Scenedesmus obliquus grown heterotrophically on 13C-labelled glucose and acetate [23].
  • Intermediates of tocopherol biosynthesis in the unicellular alga Scenedesmus obliquus. The presence of three isomeric methylphytylbenzoquinones [24].
  • Biosynthesis of isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehyde 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus [23].
  • Three isomers of methylphytylbenzoquinone have been isolated from lipids of the unicellular alga Scenedesmus obliquus, the most abundant being 2-methyl-6-phytylbenzoquinone (65% of the total) [24].
  • The "high-affinity Mn-binding site" in Mn-depleted photosystem II (PS II) membrane fragments isolated from Scenedesmus obliquus was examined by using the diphenylcarbazide (DPC)/Mn2+ non-competitive inhibition assay [Preston, C., & Seibert, M. (1991) Biochemistry (preceding paper in this issue)] [25].

Gene context of Scenedesmus


Analytical, diagnostic and therapeutic context of Scenedesmus

  • Modulated PAM fluorometry and Plant Efficiency Analyser methods were used to investigate photosynthetic fluorescence parameters of alga Scenedesmus obliquus exposed to inhibitory effect of fungicides copper sulphate and fludioxonil (N-(4-nitrophenyl)-N'-propyl-uree) [31].


  1. Quantitative structure-activity analysis of the algae toxicity of nitroaromatic compounds. Schmitt, H., Altenburger, R., Jastorff, B., Schüürmann, G. Chem. Res. Toxicol. (2000) [Pubmed]
  2. The cell content and secretion of water-soluble vitamins by several freshwater algae. Aaronson, S., Dhawale, S.W., Patni, N.J., DeAngelis, B., Frank, O., Baker, H. Arch. Microbiol. (1977) [Pubmed]
  3. Life history consequences of sterol availability in the aquatic keystone species Daphnia. Martin-Creuzburg, D., Wacker, A., von Elert, E. Oecologia (2005) [Pubmed]
  4. DNA photorepair: chromophore composition and function in two classes of DNA photolyases. Jorns, M.S. Biofactors (1990) [Pubmed]
  5. Toxicity of fluoranthene and its biodegradation metabolites to aquatic organisms. Sepic, E., Bricelj, M., Leskovsek, H. Chemosphere (2003) [Pubmed]
  6. Intranuclear complexes in a copper-tolerant green alga. Silverberg, B.A., Stokes, P.M., Ferstenberg, L.B. J. Cell Biol. (1976) [Pubmed]
  7. Genetic dissection of carotenoid synthesis in arabidopsis defines plastoquinone as an essential component of phytoene desaturation. Norris, S.R., Barrette, T.R., DellaPenna, D. Plant Cell (1995) [Pubmed]
  8. The D1 C-terminal processing protease of photosystem II from Scenedesmus obliquus. Protein purification and gene characterization in wild type and processing mutants. Trost, J.T., Chisholm, D.A., Jordan, D.B., Diner, B.A. J. Biol. Chem. (1997) [Pubmed]
  9. The PQ/PQH2 ratio and occupancy of photosystem II-QB site by plastoquinone control the degradation of D1 protein during photoinhibition in vivo. Gong, H.S., Ohad, I. J. Biol. Chem. (1991) [Pubmed]
  10. Group II intron splicing in Escherichia coli: phenotypes of cis-acting mutations resemble splicing defects observed in organelle RNA processing. Holländer, V., Kück, U. Nucleic Acids Res. (1999) [Pubmed]
  11. Toxicity and bioaccumulation of cadmium in the colonial green alga Scenedesmus obliquus. Cain, J.R., Paschal, D.C., Hayden, C.M. Arch. Environ. Contam. Toxicol. (1980) [Pubmed]
  12. Toxicity of cypermethrin on growth, pigments, and superoxide dismutase of Scenedesmus obliquus. Li, X., Ping, X., Xiumei, S., Zhenbin, W., Liqiang, X. Ecotoxicol. Environ. Saf. (2005) [Pubmed]
  13. Tolerance to mercury chloride in Scenedesmus strains. Capolino, E., Tredici, M., Pepi, M., Baldi, F. Biometals (1997) [Pubmed]
  14. Mode of bleaching phytotoxicity of herbicidal diphenylpyrrolidinones. Ogawa, H., Yamada, I., Arai, K., Hirase, K., Moriyasu, K., Schneider, C., Sandmann, G., Böger, P., Wakabayashi, K. Pest Manag. Sci. (2001) [Pubmed]
  15. Toxicity of sulfonylurea herbicides to the green alga Scenedesmus vacuolatus: predictability of combination effects. Junghans, M., Backhaus, T., Faust, M., Scholze, M., Grimme, L.H. Bulletin of environmental contamination and toxicology. (2003) [Pubmed]
  16. Correct in vivo RNA splicing of a mitochondrial intron in algal chloroplasts. Herdenberger, F., Holländer, V., Kück, U. Nucleic Acids Res. (1994) [Pubmed]
  17. The nucleotide sequence of Scenedesmus obliquus chloroplast elongator methionine-accepting tRNA. McCoy, J.M., Keene, N.M., Jones, D.S. Biochem. J. (1986) [Pubmed]
  18. DNA sequence analysis of the complete mitochondrial genome of the green alga Scenedesmus obliquus: evidence for UAG being a leucine and UCA being a non-sense codon. Kück, U., Jekosch, K., Holzamer, P. Gene (2000) [Pubmed]
  19. Effects of diazepam on photosynthesis, respiration, rubidium uptake, and finestructure of Scenedesmus obliquus in synchronous cultures. Ober, K. Arch. Microbiol. (1975) [Pubmed]
  20. Biotransformation of 1-naphthalenesulfonic acid by the green alga Scenedesmus obliquus. Kneifel, H., Elmendorff, K., Hegewald, E., Soeder, C.J. Arch. Microbiol. (1997) [Pubmed]
  21. Adenine inhibition of the synthesis of photosynthetic membranes in the chloroplast of Scenedesmus obliquus grown in the dark. Abeliovich, A., Dickbuk, S. J. Bacteriol. (1979) [Pubmed]
  22. A new alternative non-mevalonate pathway for isoprenoid biosynthesis in eubacteria and plants. Paseshnichenko, V.A. Biochemistry Mosc. (1998) [Pubmed]
  23. Biosynthesis of isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehyde 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus. Schwender, J., Seemann, M., Lichtenthaler, H.K., Rohmer, M. Biochem. J. (1996) [Pubmed]
  24. Intermediates of tocopherol biosynthesis in the unicellular alga Scenedesmus obliquus. The presence of three isomeric methylphytylbenzoquinones. Henry, A., Powls, R., Pennock, J.F. Biochem. J. (1987) [Pubmed]
  25. Protease treatments of photosystem II membrane fragments reveal that there are four separate high-affinity Mn-binding sites. Preston, C., Seibert, M. Biochemistry (1991) [Pubmed]
  26. Properties of a multimeric protein complex from chloroplasts possessing potential activities of NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase and phosphoribulokinase. Nicholson, S., Easterby, J.S., Powls, R. Eur. J. Biochem. (1987) [Pubmed]
  27. The carboxyl modifier 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC) inhibits half of the high-affinity Mn-binding site in photosystem II membrane fragments. Preston, C., Seibert, M. Biochemistry (1991) [Pubmed]
  28. Redox control of hydrogenase activity in the green alga Scenedesmus obliquus by thioredoxin and other thiols. Wünschiers, R., Heide, H., Follmann, H., Senger, H., Schulz, R. FEBS Lett. (1999) [Pubmed]
  29. Pyrene-induced changes of glutathione-S-transferase activities in different microalgal species. Lei, A.P., Wong, Y.S., Tam, N.F. Chemosphere (2003) [Pubmed]
  30. Complex group-I introns in nuclear SSU rDNA of red and green algae: evidence of homing-endonuclease pseudogenes in the Bangiophyceae. Haugen, P., Huss, V.A., Nielsen, H., Johansen, S. Curr. Genet. (1999) [Pubmed]
  31. Determination of photosynthetic and enzymatic biomarkers sensitivity used to evaluate toxic effects of copper and fludioxonil in alga Scenedesmus obliquus. Dewez, D., Geoffroy, L., Vernet, G., Popovic, R. Aquat. Toxicol. (2005) [Pubmed]
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