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Chemical Compound Review

Thymelol     7-hydroxy-6-methoxy-3-(2- oxochromen-7...

Synonyms: Daphnoretin, Dephnoretin, AC1NQYF2, CHEMBL508494, Bio-0323, ...
 
 
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Disease relevance of TNP00178

 

High impact information on TNP00178

 

Biological context of TNP00178

 

Anatomical context of TNP00178

 

Associations of TNP00178 with other chemical compounds

 

Gene context of TNP00178

 

Analytical, diagnostic and therapeutic context of TNP00178

  • Orthogonal test design for optimization of supercritical fluid extraction of daphnoretin, 7-methoxy-daphnoretin and 1,5-diphenyl-1-pentanone from Stellera chamaejasme L. and subsequent isolation by high-speed counter-current chromatography [5].
  • In this study, we developed an automated blood sampling system coupled to a simple and sensitive HPLC system to determine plasma concentration of daphnoretin in rats [6].
  • Measurement of daphnoretin in plasma of freely moving rat by liquid chromatography [6].

References

  1. Identification of a protein kinase C (PKC) activator, daphnoretin, that suppresses hepatitis B virus gene expression in human hepatoma cells. Chen, H.C., Chou, C.K., Kuo, Y.H., Yeh, S.F. Biochem. Pharmacol. (1996) [Pubmed]
  2. Antitumor agents LIV: The effects of daphnoretin on in vitro protein synthesis of Ehrlich ascites carcinoma cells and other tissues. Liou, Y.F., Hall, I.H., Lee, K.H. Journal of pharmaceutical sciences. (1982) [Pubmed]
  3. Antitumor agents LIII: The effects of daphnoretin on nucleic acid and protein synthesis of Ehrlich ascites tumor cells. Hall, I.H., Tagahara, K., Lee, K.H. Journal of pharmaceutical sciences. (1982) [Pubmed]
  4. Daphnoretin, a new protein kinase C activator isolated from Wikstroemia indica C.A. Mey. Ko, F.N., Chang, Y.L., Kuo, Y.H., Lin, Y.L., Teng, C.M. Biochem. J. (1993) [Pubmed]
  5. Orthogonal test design for optimization of supercritical fluid extraction of daphnoretin, 7-methoxy-daphnoretin and 1,5-diphenyl-1-pentanone from Stellera chamaejasme L. and subsequent isolation by high-speed counter-current chromatography. Peng, J., Dong, F., Xu, Q., Xu, Y., Qi, Y., Han, X., Xu, L., Fan, G., Liu, K. Journal of chromatography. A (2006) [Pubmed]
  6. Measurement of daphnoretin in plasma of freely moving rat by liquid chromatography. Lin, L.C., Yang, K.Y., Chen, Y.F., Wang, S.C., Tsai, T.H. Journal of chromatography. A. (2005) [Pubmed]
  7. Daphnoretin-induced respiratory burst in rat neutrophils is, probably, mainly through protein kinase C activation. Wang, J.P., Raung, S.L., Kuo, Y.H., Teng, C.M. Eur. J. Pharmacol. (1995) [Pubmed]
  8. Potential antitumor agents: a cytotoxic cardenolide from Coronilla varia L. Williams, M., Cassady, J.M. Journal of pharmaceutical sciences. (1976) [Pubmed]
  9. A new biscoumarin glucoside ester from ruta chalepensis cell cultures. Fischer, H., Römer, A., Ulbrich, B., Arens, H. Planta Med. (1988) [Pubmed]
  10. (+)-Nortrachelogenin, a new pharmacologically active lignan from Wikstroemia indica. Kato, A., Hashimoto, Y., Kidokoro, M. J. Nat. Prod. (1979) [Pubmed]
 
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