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Chemical Compound Review

Seocalcitol     (1S,3S,5Z)-5-[(2E)-2- [(1R,3aR,7aR)-1-[(2S...

Synonyms: AC1NRAXQ, CHEMBL1908376, CS-0398, EB-1089, HY-32341, ...
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Disease relevance of Seocalcitol


High impact information on Seocalcitol


Biological context of Seocalcitol


Associations of Seocalcitol with other chemical compounds


  1. A phase II trial of the vitamin D analogue Seocalcitol (EB1089) in patients with inoperable pancreatic cancer. Evans, T.R., Colston, K.W., Lofts, F.J., Cunningham, D., Anthoney, D.A., Gogas, H., de Bono, J.S., Hamberg, K.J., Skov, T., Mansi, J.L. Br. J. Cancer (2002) [Pubmed]
  2. A phase II study of the vitamin D analogue Seocalcitol in patients with inoperable hepatocellular carcinoma. Dalhoff, K., Dancey, J., Astrup, L., Skovsgaard, T., Hamberg, K.J., Lofts, F.J., Rosmorduc, O., Erlinger, S., Bach Hansen, J., Steward, W.P., Skov, T., Burcharth, F., Evans, T.R. Br. J. Cancer (2003) [Pubmed]
  3. Effects of Seocalcitol (EB1089) on nitrosomethyl urea-induced rat mammary tumors. Colston, K.W., Pirianov, G., Bramm, E., Hamberg, K.J., Binderup, L. Breast Cancer Res. Treat. (2003) [Pubmed]
  4. MCF-7/VD(R): a new vitamin D resistant cell line. Hansen, C.M., Rohde, L., Madsen, M.W., Hansen, D., Colston, K.W., Pirianov, G., Holm, P.K., Binderup, L. J. Cell. Biochem. (2001) [Pubmed]
  5. Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile. Jenner, R.G., Maillard, K., Cattini, N., Weiss, R.A., Boshoff, C., Wooster, R., Kellam, P. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  6. Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089). Narayanan, R., Allen, M.R., Gaddy, D., Bloomfield, S.A., Smith, C.L., Weigel, N.L. Bone (2004) [Pubmed]
  7. Bioavailability of Seocalcitol IV: Evaluation of Lymphatic Transport in Conscious Rats. Grove, M., Nielsen, J.L., Pedersen, G.P., M??llertz, A. Pharm. Res. (2006) [Pubmed]
  8. The tissue-specific distribution of 3H-seocalcitol (EB 1089) and 3H-calcitriol in rats. Kissmeyer, A.M., Nielsen, J.L., Binderup, L. J. Steroid Biochem. Mol. Biol. (2004) [Pubmed]
  9. Pharmacokinetics and metabolism of a vitamin D analogue (Seocalcitol) in rat and minipig. Kissmeyer, A.M., Mortensen, J.T. Xenobiotica (2000) [Pubmed]
  10. Effects of calcitriol, seocalcitol, and medium-chain triglyceride on a canine transitional cell carcinoma cell line. Kaewsakhorn, T., Kisseberth, W.C., Capen, C.C., Hayes, K.A., Calverley, M.J., Inpanbutr, N. Anticancer Res. (2005) [Pubmed]
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