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Chemical Compound Review

AC1NSMWS     (6Z,9Z,12Z,15Z)-octadeca- 6,9,12,15...

Synonyms: Moroctic acid, CHEMBL484430, CHEBI:32389, HMDB06547, LMFA01030357, ...
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Disease relevance of Stearidonic acid


High impact information on Stearidonic acid


Anatomical context of Stearidonic acid

  • To illuminate the underlying processes, we studied the conversions of stearidonic acid, 18:4(n-3), and its elongation product, 20:4(n-3), in TF cells and also in a cell line, AS, derived from Atlantic salmon (Salmo salar), by adding unlabelled (25 microM), U-14C (1 microM) or deuterated (d5; 25 microM) fatty acids [7].

Associations of Stearidonic acid with other chemical compounds


Analytical, diagnostic and therapeutic context of Stearidonic acid


  1. Comparison of stearidonic acid and alpha-linolenic acid on PGE2 production and COX-2 protein levels in MDA-MB-231 breast cancer cell cultures. Horia, E., Watkins, B.A. J. Nutr. Biochem. (2005) [Pubmed]
  2. Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids. Parker-Barnes, J.M., Das, T., Bobik, E., Leonard, A.E., Thurmond, J.M., Chaung, L.T., Huang, Y.S., Mukerji, P. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  3. Identification of Primula "front-end" desaturases with distinct n-6 or n-3 substrate preferences. Sayanova, O., Haslam, R., Venegas-Caler??n, M., Napier, J.A. Planta (2006) [Pubmed]
  4. Dietary echium oil increases plasma and neutrophil long-chain (n-3) fatty acids and lowers serum triacylglycerols in hypertriglyceridemic humans. Surette, M.E., Edens, M., Chilton, F.H., Tramposch, K.M. J. Nutr. (2004) [Pubmed]
  5. Comparison of the effects of dietary alpha-linolenic, stearidonic, and eicosapentaenoic acids on production of inflammatory mediators in mice. Ishihara, K., Komatsu, W., Saito, H., Shinohara, K. Lipids (2002) [Pubmed]
  6. Stearidonic acid, an inhibitor of the 5-lipoxygenase pathway. A comparison with timnodonic and dihomogammalinolenic acid. Guichardant, M., Traitler, H., Spielmann, D., Sprecher, H., Finot, P.A. Lipids (1993) [Pubmed]
  7. Low C18 to C20 fatty acid elongase activity and limited conversion of stearidonic acid, 18:4(n-3), to eicosapentaenoic acid, 20:5(n-3), in a cell line from the turbot, Scophthalmus maximus. Ghioni, C., Tocher, D.R., Bell, M.V., Dick, J.R., Sargent, J.R. Biochim. Biophys. Acta (1999) [Pubmed]
  8. Purification of stearidonic acid (18:4(n-3)) and hexadecatetraenoic acid (16:4(n-3)) from algal fatty acid with lipase and medium pressure liquid chromatography. Ishihara, K., Murata, M., Kaneniwa, M., Saito, H., Komatsu, W., Shinohara, K. Biosci. Biotechnol. Biochem. (2000) [Pubmed]
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