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Chemical Compound Review

zlchem 848     naphthalene-2,3-diamine

Synonyms: PubChem15532, SureCN139321, CCRIS 8399, AG-J-00807, ACMC-209p8c, ...
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Disease relevance of NSC 62692


High impact information on NSC 62692

  • Furthermore, elicited neutrophils (2 x 10(6) cells) were capable of N-nitrosating 2,3-diaminonaphthalene to yield its nitrosamine derivative 1-naphtho-2,3-triazole (282 +/- 12 nmol/L) in a time- and cell-dependent pattern similar to that of nitrite production [2].
  • S-nitrosoglutathione (GSNO) denitrosation activity of recombinant human protein disulfide isomerase (PDI) has been kinetically characterized by monitoring the loss of the S-NO absorbance, using a NO electrode, and with the aid of the fluorogenic NOx probe 2,3-diaminonaphthalene [3].
  • Growth suppression correlated with nitrite formation and nitrosation of 2,3-diaminonaphthalene elicited by stimulated murine macrophages [4].
  • Nitrite production (2,3-diaminonaphthalene fluorometric assay) increased 12-, 16-, and 23-fold at 3.3, 10, and 30 dyn/cm(2), respectively, compared with static control cultures [5].
  • A specimen or aqueous standard, 100 microL, is digested with 0.5 mL of HNO3/HCIO4 (4/1 by vol, at 190 degrees C for 90 min), reduced with 0.5 mL of concentrated HCI (150 degrees C, 30 min), and complexed with 0.5 mL of 6.3 mmol/L 2,3-diaminonaphthalene (DAN) reagent in the presence of EDTA (60 degrees C, 30 min) [6].

Biological context of NSC 62692


Anatomical context of NSC 62692


Associations of NSC 62692 with other chemical compounds


Analytical, diagnostic and therapeutic context of NSC 62692


  1. Mechanism for nitrosation of 2,3-diaminonaphthalene by Escherichia coli: enzymatic production of NO followed by O2-dependent chemical nitrosation. Ji, X.B., Hollocher, T.C. Appl. Environ. Microbiol. (1988) [Pubmed]
  2. Neutrophil-mediated nitrosamine formation: role of nitric oxide in rats. Grisham, M.B., Ware, K., Gilleland, H.E., Gilleland, L.B., Abell, C.L., Yamada, T. Gastroenterology (1992) [Pubmed]
  3. Characterization of the S-denitrosation activity of protein disulfide isomerase. Sliskovic, I., Raturi, A., Mutus, B. J. Biol. Chem. (2005) [Pubmed]
  4. Comparison of control of Listeria by nitric oxide redox chemistry from murine macrophages and NO donors: insights into listeriocidal activity of oxidative and nitrosative stress. Ogawa, R., Pacelli, R., Espey, M.G., Miranda, K.M., Friedman, N., Kim, S.M., Cox, G., Mitchell, J.B., Wink, D.A., Russo, A. Free Radic. Biol. Med. (2001) [Pubmed]
  5. Shear stress-mediated NO production in inner medullary collecting duct cells. Cai, Z., Xin, J., Pollock, D.M., Pollock, J.S. Am. J. Physiol. Renal Physiol. (2000) [Pubmed]
  6. Simplified fluorometric assay of total selenium in plasma and urine. Sheehan, T.M., Gao, M. Clin. Chem. (1990) [Pubmed]
  7. Determination of selenium in human serum by liquid chromatography/electron capture atmospheric pressure chemical ionization mass spectrometry after acid digestion and derivatization using 2,3-diaminonaphthalene. Ando, M., Takizawa, M., Suwabe, S., Yamato, S., Shimada, K. European journal of mass spectrometry (Chichester, England) (2003) [Pubmed]
  8. Modification of the cadmium reduction assay for detection of nitrite production using fluorescence indicator 2,3-diaminonaphthalene. Casey, T.E., Hilderman, R.H. Nitric Oxide (2000) [Pubmed]
  9. Intensity-independent fluorometric detection of cellular nitric oxide release. Andrew, P.J., Auer, M., Lindley, I.J., Kauffmann, H.F., Kungl, A.J. FEBS Lett. (1997) [Pubmed]
  10. Oxidative conversion of 6-nitrocatecholamines to nitrosating products: a possible contributory factor in nitric oxide and catecholamine neurotoxicity associated with oxidative stress and acidosis. Palumbo, A., Napolitano, A., Carraturo, A., Russo, G.L., d'Ischia, M. Chem. Res. Toxicol. (2001) [Pubmed]
  11. Insulin-stimulated endothelial nitric oxide release is calcium independent and mediated via protein kinase B. Hartell, N.A., Archer, H.E., Bailey, C.J. Biochem. Pharmacol. (2005) [Pubmed]
  12. Effects of superoxide on nitric oxide-dependent N-nitrosation reactions. Miles, A.M., Gibson, M.F., Kirshina, M., Cook, J.C., Pacelli, R., Wink, D., Grisham, M.B. Free Radic. Res. (1995) [Pubmed]
  13. Measurement of 4,5-dioxovaleric acid by high-performance liquid chromatography and fluorescence detection. Ummus, R.E., Onuki, J., Dörnemann, D., Medeiros, M.H., Di Mascio, P. J. Chromatogr. B Biomed. Sci. Appl. (1999) [Pubmed]
  14. Effects of glycemic control on plasma 3-deoxyglucosone levels in NIDDM patients. Hamada, Y., Nakamura, J., Fujisawa, H., Yago, H., Nakashima, E., Koh, N., Hotta, N. Diabetes Care (1997) [Pubmed]
  15. Acrolein produces nitric oxide through the elevation of intracellular calcium levels to induce apoptosis in human umbilical vein endothelial cells: implications for smoke angiopathy. Misonou, Y., Asahi, M., Yokoe, S., Miyoshi, E., Taniguchi, N. Nitric Oxide (2006) [Pubmed]
  16. Monitoring of feeds selenium status in a southeast region of Romania. Serdaru, M., Vladescu, L., Avram, N. J. Agric. Food Chem. (2003) [Pubmed]
  17. Neutron activation analysis of selenium and 17 elements in sediment. Tamari, Y. Radioisotopes (1979) [Pubmed]
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