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Chemical Compound Review

threonine     (2R,3R)-2-amino-3-hydroxy- butanoic acid

Synonyms: AmbotzHAA1187, PubChem12340, PubChem19051, CHEMBL319354, AG-E-74591, ...
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Disease relevance of threonine

  • Because the polymerase and the surface gene overlap, the introduction of these mutations affected the secretion of hepatitis B surface antigen (HBsAg), namely 4 variants (I, V, L, and R) secreted HBsAg, whereas 3 variants (A, K, and T) did not [1].

High impact information on threonine


  1. YMDD motif in hepatitis B virus DNA polymerase influences on replication and lamivudine resistance: A study by in vitro full-length viral DNA transfection. Ono-Nita, S.K., Kato, N., Shiratori, Y., Masaki, T., Lan, K.H., Carrilho, F.J., Omata, M. Hepatology (1999) [Pubmed]
  2. Solid-phase glycosylation of peptide templates and on-bead MAS-NMR analysis: perspectives for glycopeptide libraries. Halkes, K.M., Gotfredsen, C.H., Grøtli, M., Miranda, L.P., Duus, J.O., Meldal, M. Chemistry (Weinheim an der Bergstrasse, Germany) (2001) [Pubmed]
  3. The kinetics of diastereomeric amino acids with o-phthaldialdehyde. Meyer, M.W., Meyer, V.R., Ramseyer, S. Chirality. (1991) [Pubmed]
  4. Characterization of a higher plant herbicide-resistant phytoene desaturase and its use as a selectable marker. Arias, R.S., Dayan, F.E., Michel, A., Howell, J., Scheffler, B.E. Plant Biotechnol. J. (2006) [Pubmed]
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