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Gene Review

Emilin1  -  elastin microfibril interfacer 1

Mus musculus

Synonyms: 5830419M17Rik, AW229038, BB105748, EMILIN-1, Elastin microfibril interface-located protein 1, ...
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Disease relevance of Emilin1

  • Of 10 monoclonal antibodies which can immunoprecipitate intracellular VZV antigens and virion glycoproteins, 1 (termed gA) reacted with gp105, 1 (termed gB) reacted with gp115 (intracellular only), gp62, and gp57, and 8 (termed gC) reacted with gp92, gp83, gp52, and gp45 [1].
  • Further analysis of the localization of the epitope was obtained by CNBr cleavage and partial digestion of gp 115 with Staphylococcus aureus V8 protease and alpha-chymotrypsin digestion [2].

High impact information on Emilin1


Biological context of Emilin1


Anatomical context of Emilin1


Associations of Emilin1 with chemical compounds


Analytical, diagnostic and therapeutic context of Emilin1


  1. Three major glycoprotein genes of varicella-zoster virus whose products have neutralization epitopes. Keller, P.M., Neff, B.J., Ellis, R.W. J. Virol. (1984) [Pubmed]
  2. Monoclonal antibodies against chick gp 115, a matrix glycoprotein with broad distribution. Colombatti, A., Bressan, G.M., Volpin, D., Castellani, I. Coll. Relat. Res. (1985) [Pubmed]
  3. Emilin1 links TGF-beta maturation to blood pressure homeostasis. Zacchigna, L., Vecchione, C., Notte, A., Cordenonsi, M., Dupont, S., Maretto, S., Cifelli, G., Ferrari, A., Maffei, A., Fabbro, C., Braghetta, P., Marino, G., Selvetella, G., Aretini, A., Colonnese, C., Bettarini, U., Russo, G., Soligo, S., Adorno, M., Bonaldo, P., Volpin, D., Piccolo, S., Lembo, G., Bressan, G.M. Cell (2006) [Pubmed]
  4. Analysis of regulatory regions of Emilin1 gene and their combinatorial contribution to tissue-specific transcription. Fabbro, C., de Gemmis, P., Braghetta, P., Colombatti, A., Volpin, D., Bonaldo, P., Bressan, G.M. J. Biol. Chem. (2005) [Pubmed]
  5. An emilin family extracellular matrix protein identified in the cochlear basilar membrane. Amma, L.L., Goodyear, R., Faris, J.S., Jones, I., Ng, L., Richardson, G., Forrest, D. Mol. Cell. Neurosci. (2003) [Pubmed]
  6. Expression of the EMILIN-1 gene during mouse development. Braghetta, P., Ferrari, A., de Gemmis, P., Zanetti, M., Volpin, D., Bonaldo, P., Bressan, G.M. Matrix Biol. (2002) [Pubmed]
  7. Developmental expression and biochemical characterization of Emu family members. Leimeister, C., Steidl, C., Schumacher, N., Erhard, S., Gessler, M. Dev. Biol. (2002) [Pubmed]
  8. EMILIN-1 deficiency induces elastogenesis and vascular cell defects. Zanetti, M., Braghetta, P., Sabatelli, P., Mura, I., Doliana, R., Colombatti, A., Volpin, D., Bonaldo, P., Bressan, G.M. Mol. Cell. Biol. (2004) [Pubmed]
  9. Overlapping, complementary and site-specific expression pattern of genes of the EMILIN/Multimerin family. Braghetta, P., Ferrari, A., De Gemmis, P., Zanetti, M., Volpin, D., Bonaldo, P., Bressan, G.M. Matrix Biol. (2004) [Pubmed]
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