The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

phoR  -  phosphate regulon sensor protein

Escherichia coli CFT073

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of phoR


High impact information on phoR

  • B. subtilis phoR was placed in the Bacillus chromosome under the control of the Pspac promoter, which is IPTG inducible [2].
  • The results suggest that phoB and phoR constitute a single operon whose promoter is located proximal to phoB [3].
  • We constructed recombinant plasmids that contain a phoR'-'lacZ fusion gene to study the regulation of phoR expression [3].
  • Regulation of the phosphate regulon of Escherichia coli: analysis of mutant phoB and phoR genes causing different phenotypes [4].
  • Although an operon structure was suggested previously (K. Makino, H. Shinagawa, M. Amemura, and A. Nakata, J. Mol. Biol. 190:37-44 and 192:549-556, 1986), previous results showed only that phoR gene expression during phosphate limitation is dependent on the upstream phoB promoter [5].

Biological context of phoR

  • Mutation in any one of the three regulator genes (phoR, T and S) is known to make the cell constitutive for APase synthesis and enable the mutants to form larger colonies on beta-glycerophosphate plate under the condition of excess inorganic phosphate [6].

Analytical, diagnostic and therapeutic context of phoR

  • In Southern blot analysis with specific probes from very conserved regions of the phoR and phoB genes from Escherichia coli, a positive hybridization with S. acidocaldarius BC65 chromosomal DNA fragments was found [7].


WikiGenes - Universities