Gene Review:
MAP3K2 - mitogen-activated protein kinase kinase...
Homo sapiens
Synonyms:
MAPK/ERK kinase kinase 2, MAPKKK2, MEK kinase 2, MEKK 2, MEKK2, ...
- Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways. Zhang, D., Facchinetti, V., Wang, X., Huang, Q., Qin, J., Su, B. EMBO J. (2006)
- Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells. Chayama, K., Papst, P.J., Garrington, T.P., Pratt, J.C., Ishizuka, T., Webb, S., Ganiatsas, S., Zon, L.I., Sun, W., Johnson, G.L., Gelfand, E.W. Proc. Natl. Acad. Sci. U.S.A. (2001)
- PB1 domain-dependent signaling complex is required for extracellular signal-regulated kinase 5 activation. Nakamura, K., Uhlik, M.T., Johnson, N.L., Hahn, K.M., Johnson, G.L. Mol. Cell. Biol. (2006)
- Dimerization through the catalytic domain is essential for MEKK2 activation. Cheng, J., Yu, L., Zhang, D., Huang, Q., Spencer, D., Su, B. J. Biol. Chem. (2005)
- In vitro activity of MEKK2 and MEKK3 in detergents is a function of a valine to serine difference in the catalytic domain. Widmann, C., Sather, S., Oyer, R., Johnson, G.L., Dreskin, S.C. Biochim. Biophys. Acta (2001)
- Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis. Hammaker, D.R., Boyle, D.L., Chabaud-Riou, M., Firestein, G.S. J. Immunol. (2004)
- Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation. Cheng, J., Yang, J., Xia, Y., Karin, M., Su, B. Mol. Cell. Biol. (2000)
- WNK1 activates ERK5 by an MEKK2/3-dependent mechanism. Xu, B.E., Stippec, S., Lenertz, L., Lee, B.H., Zhang, W., Lee, Y.K., Cobb, M.H. J. Biol. Chem. (2004)
- The TAO of MEKK. Schlesinger, T.K., Fanger, G.R., Yujiri, T., Johnson, G.L. Front. Biosci. (1998)
- Expression cloning screen for modifiers of amyloid precursor protein shedding. Schöbel, S., Neumann, S., Seed, B., Lichtenthaler, S.F. Int. J. Dev. Neurosci. (2006)