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Gene Review

Pdia4  -  protein disulfide isomerase family A,...

Rattus norvegicus

Synonyms: CaBP2, Cabp2, Calcium-binding protein 2, ER protein 70, ER protein 72, ...
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Disease relevance of Pdia4


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Anatomical context of Pdia4


Associations of Pdia4 with chemical compounds


Physical interactions of Pdia4

  • In contrast, after cross-linking, there was a large increase in the amount of ERp72 and grp94 that coimmunoprecipitated with anti-Tg antibodies, although there was only a slight increase in BiP [5].


  1. CaBP2 is a rat homolog of ERp72 with proteindisulfide isomerase activity. Van, P.N., Rupp, K., Lampen, A., Söling, H.D. Eur. J. Biochem. (1993) [Pubmed]
  2. Erp72 expression activated by transient cerebral ischemia or disturbance of neuronal endoplasmic reticulum calcium stores. Paschen, W., Gissel, C., Linden, T., Doutheil, J. Metabolic brain disease. (1998) [Pubmed]
  3. Perturbations in maturation of secretory proteins and their association with endoplasmic reticulum chaperones in a cell culture model for epithelial ischemia. Kuznetsov, G., Bush, K.T., Zhang, P.L., Nigam, S.K. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  4. The assembly and secretion of apolipoprotein B-48-containing very low density lipoproteins in McA-RH7777 cells. Stillemark, P., Borén, J., Andersson, M., Larsson, T., Rustaeus, S., Karlsson, K.A., Olofsson, S.O. J. Biol. Chem. (2000) [Pubmed]
  5. Several endoplasmic reticulum stress proteins, including ERp72, interact with thyroglobulin during its maturation. Kuznetsov, G., Chen, L.B., Nigam, S.K. J. Biol. Chem. (1994) [Pubmed]
  6. A homologue of the calcium-binding disulfide isomerase CaBP1 is expressed in the developing CNS of Drosophila melanogaster. Li, Y., Musacchio, M., Finkelstein, R. Dev. Genet. (1998) [Pubmed]
  7. Expression of an HSP110 family, ischemia-responsive protein (irp94), in the rat brain after transient forebrain ischemia. Koh, H.S., Moon, I.S., Lee, Y.H., Shong, M., Kwon, O.Y. Z. Naturforsch., C, J. Biosci. (2000) [Pubmed]
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