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Gene Review

OXER1  -  oxoeicosanoid (OXE) receptor 1

Homo sapiens

Synonyms: 5-oxo-ETE G-protein coupled receptor, G-protein coupled receptor 170, G-protein coupled receptor R527, G-protein coupled receptor TG1019, GPCR, ...
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High impact information on OXER1


Biological context of OXER1


Associations of OXER1 with chemical compounds


Other interactions of OXER1

  • The beta-arr2 R393E, R395E mutant also enhanced the signal window with other members of the GPCR family (neuropeptide Y type 2 receptor [NPY2-R] and TG1019 receptor) and was successfully applied in full-plate BRET(2)-based agonist and antagonist screening assays [4].


  1. Identification of a novel human eicosanoid receptor coupled to G(i/o). Hosoi, T., Koguchi, Y., Sugikawa, E., Chikada, A., Ogawa, K., Tsuda, N., Suto, N., Tsunoda, S., Taniguchi, T., Ohnuki, T. J. Biol. Chem. (2002) [Pubmed]
  2. Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils. Jones, C.E., Holden, S., Tenaillon, L., Bhatia, U., Seuwen, K., Tranter, P., Turner, J., Kettle, R., Bouhelal, R., Charlton, S., Nirmala, N.R., Jarai, G., Finan, P. Mol. Pharmacol. (2003) [Pubmed]
  3. 5-Oxo-ETE analogs and the proliferation of cancer cells. O'Flaherty, J.T., Rogers, L.C., Paumi, C.M., Hantgan, R.R., Thomas, L.R., Clay, C.E., High, K., Chen, Y.Q., Willingham, M.C., Smitherman, P.K., Kute, T.E., Rao, A., Cramer, S.D., Morrow, C.S. Biochim. Biophys. Acta (2005) [Pubmed]
  4. Development of a BRET2 screening assay using beta-arrestin 2 mutants. Vrecl, M., Jorgensen, R., Pogacnik, A., Heding, A. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening. (2004) [Pubmed]
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